MRI动态增强技术对鼻咽癌放疗后局部纤维化及复发的诊断研究.pdf

CHINESE JOURNAL OF CT AND MRI, NOV.2014, Vol.12, No.8 Total No.61 Diagnosis Research of Dynamic Enhanced MRI in Nasopharyngeal Carcinoma Radiofibrosis and Recurrent 论 著 LIANG Ju-xiang, DENG Xin-yuan, LUO Zhi-cheng, et al., The Peoples Hospital of Gaozhou, Gaozhou, 525200 China [Abstract] Objective This study was designed to investigate the characteristics of nasopharyngeal carcinoma recurrence (RNPC) and fibrosis (RF) on dynamic enhanced MRI动态增强技术 magnetic resonance imaging (DMRI) technology, calculated the dynamic change of T1WI signal intensity to value of RNPC and RF based on DMRI diagnosis. Methods 对鼻咽癌放疗后局 A total cases of 67 NPC patients of our hospital from March 2011 to June 2013 were 部纤维化与复发的 divided into 2 groups: 38 in RF group and 29 in RNPC group, male 45 cases, female 22 cases; Age 22-72ys, average 42±1.5ys. After conventional plain MRI scan of 诊断研究 nasopharynx, DMRI and conventional contrast enhanced T1-weighted imaging (T1WI) were performed. A circle area in tumoral parenchyma was selected as region of interest (ROI) , the T1WI signal of ROI was measured during the period from 0s to 3 mins after injection of Gb-DTPA, and the dynamic time–signal intensity curves (TIC) of the 广东省高州市人民医院 two types of turmor were obtained and compared. Maximal contrast enhancement ratio (广东 高州 525200) (MCER), Peak time to MCER (PT), The area under the concentration tim