临床相关实验室生物危害评估及生物安全水平.ppt

临床实验室生物危害评估及生物安全水平 任健康 陕西省临床检验中心 陕西省人民医院 September 25, 2003SARS work continues despite lab infection A Singaporean research institute linked to the worlds most recent SARS case of a 27-year-old man infection will abandon its work on the coronavirus.  Inappropriate laboratory procedures and a cross-contamination of West Nile virus samples with the SARS coronavirus in the laboratory led to the infection of the doctoral student. An official from Chinas Ministry of Science and Technology said Chinas research into the SARS virus and other aspects of the disease would not be affected by the accident in Singapore. Officials Concerned About SARS Infections by Lab Contamination The New York Times Last week, a World Health Organization committee that investigated the case concluded that the student most likely became infected in August through contamination in a laboratory where he worked on another virus. “Inappropriate laboratory standards and a cross-contamination of West Nile virus samples with SARS coronavirus in the laboratory led to the infection … … the Chinese University of Hong Kong halted work on growing the SARS virus for some equipment they used did not meet security standards. Institute isolated for suspected lab infection (Xinhua) Updated: 2004-04-27 09:00 Since April 22, China has reported two diagnosed and six suspected SARS cases in Beijing and east Chinas Anhui province. The Institute of Virology under the Chinese Center for Disease Prevention and Control has been isolated and all staff in contact with the affected areas have been quarantined. 职业暴露与感染 实验室工作可能发生职业暴露 职业暴露可能发生感染 实验室获得性感染 指实验室工作等活动过程中导致的工作人员及相关人员的感染，其中大约2/3的实验室获得性感染与直接接触、使用含有传染性病原体的标本或生物材料等有关 Pike对3921例报告的实验室感染分析表明，其中59%源自研究性实验室，17%发生在临床诊断性实验室 其中气溶胶是最主要的传播途径，在实验室意外引起的感染中70%是由喷溅、针刺或切割伤所致 常见的实验室感染 Most frequently reported laboratory-acquired infections in the United States and Great B ritain total no. (%) o