《Risk Factors and Surgical Outcomes for Spontaneous Rupture of Hepatocellular Carcinoma》培训课件.pptVIP

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《Risk Factors and Surgical Outcomes for Spontaneous Rupture of Hepatocellular Carcinoma》培训课件.ppt

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Discussion Survival of patients with spontaneous rupture of HCC The relationship between tumor location and the risk of spontaneous rupture of HCC was identified at the first time Our study included patients in BCLC A and B stages and underwent one-stage hepatic resection without initial treatments, and the results attained from our series are acceptable We think that one-stage hepatic resection should be recommended to patients with resectable ruptured HCC at BCLC stage A and stage B if a radical resection can be achieved. 我们推荐BCLC A和B期肝癌破裂患者接受一期手术治疗 THANKS * MST: mean survival time; MDST: mean disease-free survival time 肝癌破裂组中存在高血压和肝硬化的病人比例较高 Risk Factors and Surgical Outcomes for Spontaneous Rupture of Hepatocellular Carcinoma Yan Yiqun, MD Eastern Hepatobiliary Surgery Hospital Secondary Military Medical University, Shanghai, China Background Hepatocellular carcinoma (HCC) is one of the most common neoplasms encountered Spontaneous rupture of the tumor is one of the life-threatening complications of HCC Spontaneous occurs in 3 to 26% HCC patients High mortality rates in the range of 32 to 66.7% have been reported Miyoshi A, Kitahara K, Kohya N, et al. Hepatogastroenterology 2011. Liu CL, Fan ST, Lo CM, et al. J Clin Oncol 2001. 肝细胞癌自发性破裂较少见，一旦发生，死亡率很高 Background Very few reports of risk factors for spontaneous rupture of HCC A widely accepted hypothesis: invasion and occlusion of the hepatic veins by tumor cells Managements for ruptured HCC: emergency hepatectomy, hepatic artery ligation, suture plication, packing hemostasis and transarterial embolization Debate concerning the best approach in cases of HCC rupture Zhu LX, Wang GS, Fan ST. Br J Surg 1996. Rossetto A, Adani GL, Risaliti A, et al. World J Hepatol 2010. Buczkowski AK, Kim PT, Ho SG, et al. J Gastrointest Surg 2006. Hai L, Yong-Hong P, Yong F, et al. World J Surg 2005. 肝细胞癌自发性破裂危险因素不明确，处理措施存在争议 In our hospital, most ruptured HCC patients were found during the routine work (outpati