RD 珠江医院课件-傅强.ppt

* Europe Medtronic Intl. Trading SARL Route du Molliau 31 Case Postale CH-1131 Tolochenaz Switzerland Tel: +(41) 21.802.70.00 Fax: +(41) 21.802.79.00 Canada Medtronic of Canada Ltd. 99 Hereford Street Brampton, Ontario L6Y 0R3 Canada Tel: +1 (905) 460.3800 Fax: +1 (905) 460.3998 Toll-free: 1 (800) 268.5346 www.medtronicRDN.com Asia Pacific Medtronic Intl. Ltd. 16/F Manulife Plaza The Lee Gardens 33 Hysan Avenue Causeway Bay Hong Kong Tel: +(852) 2919.1300 Fax: +(852) 2891.6830 Latin America Medtronic USA, Inc. Doral Corporate Center II 3750 NW 87th Avenue Suite 700 Miami, FL 33178 USA Tel: +1 (305) 500.9328 Fax: +1 (786) 709.4244 * * * * * Purpose: To provide histological evidence of treatment-related renal nerve injury 6 months following RDN in a porcine experimental model. Key Points: In the nerve from the untreated vessel (left), there is a periarterial nerve bundle surrounded by a thin fibrous connective tissue sheath (perineurium) In contrast, the nerve from the treated vessel (right) has a hypercellular appearance and the perineurium has a thickened and fibrotic appearance At 6 months, there was no inflammation seen following the renal nerve injury Source: Rippy MK, Zarins, D, Barman NC, et al. Catheter-based renal sympathetic denervation: chronic preclinical evidence for renal artery safety. Clin Res Cardiol. July 2011. doi:101007s00392-011-0346-8. * * * * * * * * * * * * * * * * * * For distribution only in markets where the Symplicity? renal denervation system is approved. Not for distribution in the USA or Japan. Trademarks may be registered and are the property of their respective owners. ? 2012 Medtronic, Inc. All rights reserved. UC201205567EE For distribution only in markets where the Symplicity? renal denervation system is approved. Not for distribution in the USA or Japan. Trademarks may be registered and are the property of their respective owners. ? 2012 Medtronic, Inc. All rights reserved. UC201205567EE Catheter-Base