胰腺癌诊治指南课件.ppt

切缘的判断标准 以距切缘1mm 内有无肿瘤浸润为判断R0 或R1 切除的标准，距切缘1mm 组织内如有肿瘤细胞浸润，为R1 切除；如无肿瘤细胞浸润，为R0 切除。 胰腺癌诊治流程 * Semin Oncol. 1996 Apr;23(2):251-75. Familial pancreatic cancer: a review. Lynch HT, Smyrk T, Kern SE, This review addresses the genetic epidemiology of pancreatic cancer and updates our views on screening, surgery, chemotherapy, and genetic counseling, all of which must be used to gain value from genetic predictability of risk status. J Clin Gastroenterol. 1989 Apr;11(2):211-5. New-onset diabetes mellitus as a harbinger of pancreatic carcinoma. A case report and literature review. Rosa JA, Van Linda BM, Abourizk NN. We review the literature on the relationship between diabetes mellitus and pancreatic carcinoma with particular emphasis on situations in which recent-onset diabetes may be a harbinger of pancreatic carcinoma. N Engl J Med. 1993 May 20;328(20):1433-7. Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group. Lowenfels AB, Maisonneuve P, Cavallini G, CONCLUSIONS. The risk of pancreatic cancer is significantly elevated in subjects with chronic pancreatitis and appears to be independent of sex, country, and type of pancreatitis. * Cancer. 2002 May 1;94(9):2344-9. A prospective pancreatographic study of the prevalence of pancreatic carcinoma in patients with diabetes mellitus. Ogawa Y, Tanaka M, Inoue K, Yamaguchi K, Chijiiwa K, Mizumoto K, Tsutsu N, Nakamura Y. BACKGROUND: The correlation between diabetes mellitus and pancreatic carcinoma is well documented, but no criteria have been established for the efficient selection of a high-risk group among patients with diabetes mellitus. METHODS: Eighty-seven patients were selected prospectively from outpatients with diabetes and underwent endoscopic retrograde pancreatography (ERP) according to the authors original criteria, including the onset of diabetes after age 55 years, deterioration of diabetes or loss of body weight despite strict medical control, elevation of serum amylase