3岁内喘息疾病患儿临床特征研究.doc

3岁内喘息疾病患儿临床特征研究 　　[摘要]目的 探讨3岁内婴幼儿喘息性疾病的临床特征。 方法 选择3岁以内反复喘息患儿150例，包括毛细支气管炎85例，婴幼儿哮喘32例，喘息性支气管炎30例，先天性喉喘鸣2例，支气管异物吸入1例。入院当日至第5 天行外周血常规检测，并进行病原学检查。 结果 本研究中150例喘息患儿中感染合胞病毒、副流感病毒、腺病毒、鼻病毒及肺炎支原体的阳性率分别为32.67%、25.33 %、8.00%、5.33%和4.67%。喘预测指数（API）阳性者58例，所有患儿中有132例患儿在3～10 d内症状缓解，其余19例未见好转，其中2例喘息症状加重，需进行进一步检查和治疗。 结论 临床上对于喘息患儿应当详细检查，反复治疗不佳后应当仔细查体，做出准确诊断。 [关键词]婴儿；喘息；临床分析 [中图分类号] R725.6 [文献标识码] B [文章编号] 2095-0616（2013）14-197-03 Clinical characteristics analysis of wheezing in 3 year old infants LIU Guoqiang1 JIANG Jianru1 XIE Hairui1 LI Zengqing2 YAN Haiqing1 1.Yuexiu Children’s Hospital，Guangzhou 510115，China；2.The People’s Hospital of Guangdong， Guangzhou 510030，China [Abstract] Objective To ivestigate the clinical features of wheezing in infants. Methods 150 cases with recurrent wheezing diagnosed as asthma were enrolled in this study，including 85 cases of bronchiolitis，32 cases of asthma，30 cases of asthmatoid bronchitis，cases of congenital laryngeal stridor and 1 case of bronchial foreign bodya spiration. The blood count was analyzed on 1 day and 5th day，and the pathogenic analysis was performed. Results In this study，150 cases of wheezing children were infected with syncytial virus，parainfluenza virus，adenovirus，rhinovirus and mycoplasma pneumoniae，with the positive rate of 32.67%，25.33 %，8.00%，5.33% and 4.67%，respectively. The number of patients with positive asthma predictive index（API） was 58. In all patients，132 cases with symptoms alleviate within 3-10 d，the rest of the 19 cases showed no improvement，among which 2 cases showed worse breathing symptoms，needing further examination and treatment. Conclusion For clinical wheezing children，a detailed inspection should be given，and the physical examination should be employed after repeated treatments to make an accurate diagnosis. [Key words] Infant；Wheezing；Clinical analysis 喘息是小儿呼吸道疾病的常见症状之一，临床表现为喘息、气促、喘憋、呼吸困难等，发病机制较为复杂。婴幼儿喘息性发作性疾病与支气哮喘关系密切[1-4]，但两者发病的内在联系尚不清楚。临床上，一部分小儿因长期、反复喘息发展成哮喘，对小儿身体健康造成了严重的危害。流行