药物分析实验(药学英语).doc

Selected Experiments of Pharmaceutical Analysis （药物分析实验/供英语药学使用） Edited by Liu qian Yu Zhiguo May.2003 Preface The “Selected Experiments of Pharmaceutical Analysis” is for the students of the English Class of Pharmacy. This booklet is the second edition. It was edited by Ms Liu Qian and Mr Yu Zhiguo. The experiments included were selected from the first edition (1994, by Yu Zhiguo) and the Chinese edition (2001, by Hou Xiaohong). Liu Qian Department of Pharmaceutical Analysis May, 2003 Contents Exp.1 Tests for Generic Impurities in Glucose 厖厖厖厖厖厖厖?experime01 Exp.2 Tests for Specific Impurities 厖厖厖厖厖厖厖厖厖??experimen04 Exp.3 Assay of Compound Aapirin Tablets by Volumetric Titration Method 厖? E07 Exp.4 Assay of Di-iodohydroxyquinoline Tablets Using Oxygen Flask Combustion厖厖厖厖厖厖厖厖?ss of Pha11 Exp.5 Diphasic Titration of Organic Bases 厖厖厖厖厖厖厖厖 Using 14 Exp.6 Non-aqueous Alkalimetric Method of Quinine Sulfate 厖厖厖厖 en F16 Exp 7 The assay of medicine by Redox Titration Method 厖厖厖厖?xp 7 18 Exp.8 Double-wavelength Spectroscopic Assay of compound sulfamethoxazole tablets 厖厖厖厖厖厖厖 厖厖?ss o19 Exp.9 The validation and application of UV-spectrophotometry in the assay of preparation 厖厖厖厖厖厖厖厖厖?Phamacy22 Exp.10 The test of HPLC system suitability and application of HPLC in the assay of preparation 厖厖厖厖厖厖厖厖厖?acy24 Exp.11 The applications of GC in the assay of Chinese traditional medicinal materials 厖厖厖厖厖厖?on 厖厖厖厖27 Exp.12 The assay of drug in biological sample（I） ——The foundation and validation of analytical method ………………… 29 Exp.13 The assay of drug in biological sample（II） ——The estimation of pharmacokinetic parameter ……………………… 32 Exp.1 Tests for Generic Impurities in Glucose PURPOSE To know well the principle of tests for the generic impurities To practise the procedures of tests for impurities PROCEDURE Acidity Dissolve 2.0g in 20mL of water. Add 3 drops of phenolphthalein TS and 0.20mL of sodium hydroxide solution (0.02 mol/L). Th