icp-ms培训教材课件.ppt

Users Training on Inductively Coupled Plasma Mass Spectrometry Objectives Overview of ICP-MS ICP-MS Theory and Elan Hardware ELAN Software Fundamentals Setup and Performance Tests Parameter Optimization Method Development Quality Control Laboratory Exercises Overview of ICP-MS Section One ICP-MS Definition An analytical technique to determine Elements using Mass Spectrometry from Ions generated by an Inductively Coupled Plasma Mass spectroscopy Separation(by Mass/Charge) and measurement of the mass of individual atoms making up a given material eg. Na at mass 23 from Mg at mass 24; charge is 1 in argon plasma. 质 谱 法（Mass Spectrometry， MS） 质谱法是通过将样品转化为运动的气态离子并按质荷比(M／Z)大小进行分离并记录其信息的分析方法。所得结果以图谱表达，即所谓的质谱图（亦称质谱，Mass Spectrum）。根据质谱图提供的信息可以进行多种有机物及无机物的定性和定量分析、复杂化合物的结构分析、样品中各种同位素比的测定及固体表面的结构和组成分析等。 The Purpose of the Plasma Analytical Benefits of ICP-MS Rapid multi-element quantitative analysis Very low detection limits Rapid semi-quantitative analysis Wide dynamic range Isotopic analysis Spectral simplicity Elements Analyzed by ICP-MS Unsurpassed Detection Limits 环保行业的典型控制值 ELAN 的检出限 Detection Limits Most below 10 ppt Most elements at least 10 X better than GFAA Most elements less than 0.01 ug/L: 10 ng/L Al, As, Hg, Mg, Ti 5 ng/L Ag, Au, Ba, Cd, Cu, Co, Mn, Mo, Sn, Sb, Pb, Pt 1 ng/L All rare earth elements, Uranium and Thorium Even halogens have useful detection limits: I 0.01 ug/L Br 0.2 ug/L Cl 10 ug/L ICP-MS Spectral Simplicity Relatively few spectral interferences: most elements have only a few isotopes overlaps that do occur are predictable overlaps are correctable by evaluating other isotopes High degree of element specificity ICP-MS Applications Environmental Federal, State Water Quality/Pollution Control Clinical Blood, Urine, Serum, Isotope tracer studies Petrochemical Ultra-High Purity Chemicals Semiconductor Ultra-High Purity Chemicals Geochemical Metallurgical 何为 ICP-MS? Atom Bohr Model of Hydrogen Excitation Decay and