原发性肝癌合并脾功能亢进低剂量姑息性放射治疗的临床研究原发性肝癌合并脾功能亢进低剂量姑息性放射治疗的临床研究.pdf

Asian Case Reports in Oncology 亚洲肿瘤科病例研究, 2017, 6(4), 26-32 Published Online October 2017 in Hans. /journal/acrpo /10.12677/acrpo.2017.64005 Clinical Study of Low Dose Palliative Radiotherapy for Hepatocellular Carcinoma Complicated with Hypersplenism Shubin Wang1,2,3, Fei Yuan2,4*, Yun Wu1,2,3 1 Department of Oncology, Clinic College of Baotou City, Inner Mongolia Medical University, Baotou Inner Mongolia 2 Cancer Research Institute of Baotou Medical College, Baotou Inner Mongolia 3 Department of Oncology, The Center Hospital of Baotou City, Baotou Inner Mongolia 4 Department of Clinical Laboratory, The Center Hospital of Baotou City, Baotou Inner Mongolia th nd th Received: Aug. 8 , 2017; accepted: Aug. 22 , 2017; published: Aug. 28 , 2017 Abstract Object: To evaluate the efficacy and clinical significance of primary hepatocellular carcinoma with low dose palliative radiotherapy. Methods: A total of 28 cases of primary hepatocellular carcinoma with hypersplenism were performed by three-dimensional conformal radiotherapy in our hospit- al, with the dividing dose of 2 Gy/time, 5 times/week, and the total dose were 10 - 25 Gy. After four weeks of treatment, white blood cells, red blood cells, platelets, and the main body of the portal vein, the splenic vein and the spleen index were monitored. Results: 28 patients had mild decrease in white blood cells and platelets in the first week of treatment, then the white blood cells and platelets begin to recover. The difference of white blood cells and platelet count was statistically significant before and after radiotherapy (p 0.05). Both white blood cells and platelets were re-