咳嗽变异性哮喘的临床特征及其与典型哮喘的关系_席寅咳嗽变异性哮喘的临床特征及其与典型哮喘的关系_席寅.pdf

·150 · ()　2011 6 5 3 　Chin J Asthm a (Electronic Edition), Ju ne 2011, Vol.5, No.3 ·· 席寅　赖克方　陈如冲　罗炜　陈桥丽　王法霞　林玲　许丹媛　杨业 　　【】　　(CVA), CVA 。　2002 1 20 10 1 CVA , , 、、、、、 。、/PEF 、、。 ≥18 、《》CVA 。 , 8 。, 、 , CVA (); 。　91 CVA 74.7%, 46.2%;:63.5%、51.4%、 47.3%、37.8%、36.5%;CVA 74.7%(EOS) 2.5%。58 4.2(1 ～ 8.5), 8 (8/58, 13.8%), CVA [12 (20)v s 6(4), P0.05], 8 1 12 , 50 CVA 33 12 , (P0.05)。CVA 、EOS%、EOS%、 (P 0.05)。　CVA , , CVA 。 【】　;;; Clinical charact er ist ics of cough variant ast hma and it′s relasionship w it h the c lassic ast hma　X I Yin, LA I K e-f ang, CH EN Ru-chong , L UO Wei, CHE N Qiao-li, WAN G Fa-x ia, LIN L ing , X U Dan- uan, YA N G Ye.S tate K e L aborator of Resp iratro D isease (Guangzhou Medical College), Guangzhou I nstitute of Resp irator D isease, the F irst Af f iliated Hosp ital of Guangzhou Medica l College, Guangzhou 510120, China Corresp onding author :LA I K e-f ang , Emai l:klai @163 .com 【Abst ract】　Object ive 　T o stud the clinical characteristics of adult cough variant asthma (CVA ) and investigate the proportion of CVA developed classic asthma, explore the risk factors for the development of asthma in patients w ith CVA.Methods　The clinical characteristics and basic examinations of 9 1 CVA patients w ere retrospectivel assessed.Moderate dose budesonide or compounds of bronchodilator and corticosteroid w ere inhaled in all patients at least 8 weeks.According to whether the patient s developed asthmatic s mptoms of w heezing and d spnea through the clinic or telephone follow- up, the w ere divided into tw o groups-the pure CVA group and the asthma group.The pulmonar function parameters, eosinophil proportion of induced sputum and peripheral blood, skin prick test positive rate and ICS usage of these two groups w ere compared.Result s　The incidence of nocturnal or morning cough in 91 CVA patients