1,25(OH)2D3对宫颈癌作用的研究进展.pdf

Asian Case Reports in Oncology 亚洲肿瘤科病例研究, 2016, 5(4), 55-60 Published Online October 2016 in Hans. /journal/acrpo /10.12677/acrpo.2016.54006 The Research Progress of 1,25(OH) D 2 3 Effects on Cervical Cancer 1 2 1* 2 2 2 Wenwen Zhou , Zhenzhen Wang , Yanhong Yang , Bo Feng , Yue Feng , Qianying Li , Xiaoyu Wang2 1 The First Hospital of Qinhuangdao, Qinhuangdao Hebei 2 Postgraduate College of Chengde Medical University, Chengde Hebei st th th Received: Sep. 21 , 2016; accepted: Oct. 5 , 2016; published: Oct. 10 , 2016 Copyright © 2016 by authors and Hans Publishers Inc. This work is licensed under the Creative Commons Attribution International License (CC BY). /licenses/by/4.0/ Open Access Abstract Cervical cancer is one of common gynecological malignancies. In recent years, due to the rise of human papillomavirus (HPV) infection rates, the worsening of the human environment and other reasons, the incidence of cervical cancer showed a rapid increasing trend. Early cervical cancer is usually treated by surgery, while patients of advanced disease use surgery combining with radio- therapy and chemotherapy and other treatment options. But the chemotherapy drugs currently used in clinical practice have more serious toxicity, limiting its clinical application. Therefore, the search for drugs of new and few side effects is one of the directions of cancer research. Recent stu- dies have found that 1,25(OH)2D3 has significant