有哪些信誉好的足球投注网站- 1、本文档共6页，可阅读全部内容。
- 2、有哪些信誉好的足球投注网站（book118）网站文档一经付费（服务费），不意味着购买了该文档的版权，仅供个人/单位学习、研究之用，不得用于商业用途，未经授权，严禁复制、发行、汇编、翻译或者网络传播等，侵权必究。
- 3、本站所有内容均由合作方或网友上传，本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺！文档内容仅供研究参考，付费前请自行鉴别。如您付费，意味着您自己接受本站规则且自行承担风险，本站不退款、不进行额外附加服务；查看《如何避免下载的几个坑》。如果您已付费下载过本站文档，您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等，请点击“版权申诉”（推荐），也可以打举报电话：400-050-0827(电话支持时间：9:00-18:30)。
查看更多
9220 ()2013 10 7 20 Chin J Clinicians(Electronic Edition),October 15,2013,Vol.7,No.20
MUC1-VNTRn
MUC1-VNTRn
pVAX1-MUC1-VNTRn pVAX1-MUC1-VNTRn
T ELISPOT IFN-γT CTL
CytoTox® MUC1-VNTRn CTL Capan-2
pVAX1-MUC1-VNTRn
pVAX1-MUC1-VNTRn
pVAX1-MUC1-VNTRn CD80
CD86HLA-DR IL-12 P 0.01
MUC1-VNTR MUC1-VNTR T IFN-γ T 103.08.5
6 9
94.37.7P 0.001MUC1-VNTR MUC1-VNTR CTL Capan-2
6 9
40.123.16%37.313.95%MUC1-VNTR VNTR VNTR VNTR MUC1-cDNA
1 1 3 4
P 0.001
pVAX1-MUC1-VNTR6 panc02-MUC1
pVAX1-MUC1-VNTR VNTR VNTR P 0.01 pVAX1-MUC1-VNTRn
1 3 9
pVAX1-MUC1-VNTR6
DNA CA-15-3
Optimized construction of MUC1-VNTRn DNA vaccine and the anti-pancreatic cancer research ZHOU
Quan-bo, GONG Yuan-feng, ZHOU Yu, LIN Qing, LI Zhi-hua, CHEN Ru-fu, ZENG Bing, ZHENG Li-ping.
Department of Hepatobiliary Surgery , The Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou
510120, China
Corresponding author: CHEN Ru-fu, Email: chenrf10@
Abstract Objective MUC1-VNTRn served as a new target for pancreatic cancer immunotherapy in the
present study. We intended to screen out the most powerful pVAX1-MUC1-VNTRn DNA vaccine which showed
strongest immunogenicity in vitro and vivo. Methods pVAX1-MUC1-VNTRn were constructed and transfected
into MUC1 negative cells. The target protein of MUC1-VNTRn could be detected by Western Blot. Dendritic cell
preparation and research of biological characteristics. p
文档评论（0）