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The Role of the Respiratory Syncytial
Virus in Airway Syndromes
in Childhood
Mark L. Everard, MB ChB, FRCP, DM
Corresponding author each winter epidemic, approximately a third of a population
Mark L. Everard, MB ChB, FRCP, DM
will be infected by the virus, although in infancy infection
Department of Respiratory Medicine, Sheffield Children’s Hospital,
Western Bank, Sheffield, UK. rates run at greater than two thirds of all infants [9]. The
E-mail: m.l.everard@sheffield.ac.uk human form of the virus, which is closely related to but dis-
Current Allergy and Asthma Reports 2006, 6:97– 102 tinct from the paromyxoviruses, is related to a bovine RSV
Current Science Inc. ISSN 1529-7322 that causes LRTI in young claves kept in close proximity.
Copyright © 2006 by Current Science Inc. Soon after human RSV was first isolated nearly 50 years
ago, it was realized that this virus played a very important
role in the induction of LRTI in infancy and was the major
The majority of infants admitted to hospital in infancy
pathogen responsible for “acute bronchiolitis.” Around
with lower respiratory tract infections (LRTIs) have been
the same time, publications were starting to highlight the
infected with the respiratory syncytial
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