Orbital myositis Diagnosis and management英文电子书.pdf

Orbital Myositis: Diagnosis and Management Roberta M. S. Costa, MD, PhD, Oana M. Dumitrascu, MD, and Lynn K. Gordon, MD, PhD Corresponding author The diagnosis of orbital myositis is challenging—the Lynn K. Gordon, MD, PhD variable clinical spectrum may be mild or severe, acute or Jules Stein Eye Institute, University of California, chronic, isolated to one extraocular muscle or diffusely Los Angeles, 100 Stein Plaza, Los Angeles, CA 90095, USA. E-mail: lgordon@ucla.edu involving multiple muscles, unilateral or bilateral, and may recur [1,2]. Signs and symptoms of orbital myositis Current Allergy and Asthma Reports 2009, 9:316–323 Current Medicine Group LLC ISSN 1529-7322 may mimic other diseases of orbital and periorbital tissues Copyright © 2009 by Current Medicine Group LLC (eg, infectious disease, neoplastic lesions, other inl am- matory processes) (Table 1) [7,8]. Treatment of orbital myositis is varied and depends on the presence of associ- Orbital myositis is an inl ammatory process that ated systemic disease. In idiopathic forms, corticosteroids primarily involves the extraocular muscles and most are often used initially. In nonresponsive, recurrent, or commonly affects young adults in the third decade of chronic diseases, other immunosuppressive or biologic life, with a female predilection. Clinical characteris- therapy as w