The diagnosis and treatment of whipple’s disease英文电子书.pdf

The Diagnosis and Treatment of Whipple’s Disease Thomas Marth, MD Address standing of the etiology and pathogenesis of Whipple’s dis- Deutsche Klinik für Diagnostik, Aukammallee 33, ease, many unsolved problems remain, especially with 65191 Wiesbaden, Germany. respect to the diagnostic approach and optimized therapy E-mail: marth.gastro2@dkd-wiesbaden.de of patients. Current Allergy and Asthma Reports 2001, 1:566–571 Current Science Inc. ISSN 1529–7322 Copyright © 2001 by Current Science Inc. Clinical Presentation of Patients with Whipple’s Disease Whipple’s disease is a rare, chronic, and systemic infectious Weight loss, diarrhea, and arthropathies are the major disease caused by the ubiquitously occuring bacterium Tro- symptoms of Whipple’s disease and may be found con- pheryma whippelii. For two reasons, the disease represents comitantly in approximately 75% of patients at the time of a good example for documenting the input of modern diagnosis [1,2]. While the clinical presentation of patients molecular-based techniques into pathogenetic, diagnostic, with Whipple’s disease may vary greatly due to systemic and therapeutic concepts i