Reduction in induced pain by ultrasound may be caused by altered expression of spinal neuronal nitric oxide synthase producing neurons英文电子书.pdf

1311 ORIGINAL ARTICLE Reduction in Induced Pain by Ultrasound May Be Caused by Altered Expression of Spinal Neuronal Nitric Oxide Synthase- Producing Neurons Yueh-Ling Hsieh, PT, PhD ABSTRACT. Hsieh Y-L. Reduction in induced pain by LTRASOUND (US), A FORM of acoustic energy, is often ultrasound may be caused by altered expression of spinal Uused by physical therapists because of its deep-heat and neuronal nitric oxide synthase-producing neurons. Arch Phys pain-relieving effects.1-3 US exerts its effect on the cells and Med Rehabil 2005;86:1311-7. tissues via 2 physical mechanisms: thermal and nonthermal.4 Structures heated by US preferentially include fibrotic muscle, Objective: To examine the peripheral influence of therapeu- tendon sheaths, and major nerve roots.5 However, there is some tic ultrasound (US) on central spinal nociceptive modulation. evidence indicating that nonthermal mechanisms act through Design: Controlled, experimental animal trial. stimulating tissue regeneration, increasing the rate of cell mem- Setting: Neuroscience laboratory of a medical university in brane permeability and diffusion, increasing intracellular cal- Taiwan. 1,6,7 cium, and changing electric activity in nervous tissue. Animals: Ten male Wistar rats weighing 250 to 300g.