Comparative phytochemical characterization of three Rhodiola species英文电子书.pdf

PHYTOCHEMISTRY Phytochemistry 67 (2006) 2380–2391 /locate/phytochem Comparative phytochemical characterization of three Rhodiola species Gad G. Yousef a, Mary H. Grace a, Diana M. Cheng a, Igor V. Belolipov b, Ilya Raskin c, Mary Ann Lila a,* a Department of Natural Resources and Environmental Sciences, University of Illinois, Urbana, IL 61801, USA b Tashkent State Agrarian University, Tashkent, Uzbekistan c Biotech Center, Cook College, Rutgers University, New Brunswick, NJ 08901, USA Received 30 March 2006; received in revised form 1 June 2006 Available online 7 September 2006 Abstract In comparison to the well-recognized adaptogenic herb Rhodiola rosea, phytochemical constituents of two other Rhodiola species (R. heterodonta and R. semenovii) were elucidated and characterized. Two major phytochemical groups; phenolic and/or cyanogenic glyco- sides and proanthocyanidins, were isolated and identified in the three species. Chemical similarities among the three species were observed; however, each species displayed differences in phytochemical constituents. R. heterodonta contained a newly detected phenyl- ethanoid glycoside, heterodontoside, in addition to the known compounds tyrosol, viridoside, salidroside, and rhodiocyanoside A. Both R. heterodonta and R. rosea contained phenylethanoid/propanoid compounds that were not detected in R. semenovii. For R. semenovii, the cyanogenic gl