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161
LYSERGIC ACID DIETHYL AMIDE (LSD-25)
A CLINICAL-PSYCHOLOGICAL STUDY
CHARLES SAVAG.E
Lieutenant, MC, USN
RESEARCH REPORT
Project NM 001.056.06.02
NAVAL MEDICAL RESEARCH INSTITUTE
NATIONAL NAVAL MEDICAL CENTER
BETHESDA. MARYLAND
9 Se-ptember 1951
I
-::4. .,;.
ABSTRACT
A $t1~dy has been made of the effects of lysergic acid diethyl amide
(LSD-25 Sandoz) on the affect, c0Cn1tion, and expression of five normal
sUpjecto and 15 depressed patients. The normals received a single oral
,lose of 20.llgm. The patients received between 20-100Jigrn. by mouth daily i
for a montho Physiological reactions included rise in blood pressure and?
pulse rate, mydriasis, and incoordination; but in a few cases there was a ,:
profound fall in blood preSS1lr$ and Pulse rate. Unpleasant side effects ;
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