有哪些信誉好的足球投注网站Control of apoptosis during angiogenesis by survivin expression in endothelial cells英文电子书.pdf
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American Journal of Pathology, Vol. 156, No. 2, February 2000
Copyright © American Society for Investigative Pathology
Short Communication
Control of Apoptosis during Angiogenesis by
Survivin Expression in Endothelial Cells
Daniel S. O’Connor,* Jeffrey S. Schechner,*† ferent gene families of inhibitors and stimulators of cell
Colette Adida,* Mehdi Mesri,* death and culminates with activation of intracellular cys-
Annette L. Rothermel,* Fengzhi Li,* teine proteases, caspases.2 Aberrations of apoptosis are
Anjali K. Nath,* Jordan S. Pober,*† and known to contribute to human diseases, including can-
Dario C. Altieri* cer3 and vascular disorders.4 Specifically, aberrantly in-
creased cell death has been shown to influence athero-
From the Boyer Center for Molecular Medicine of the Department 5 6
† sclerotic plaque instability, congestive heart failure,
of Pathology* and the Department of Dermatology, Yale 7 8
coronary disease, and ischemic neuronal loss.
University School of Medicine, New Haven, Connecticut
The endothelium is one of the most critical sites for the
control of apoptosis in
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