Nanostructured lipid carriers (NLC) A potential delivery system for bioactive food molecules英文电子书.pdf

Innovative Food Science and Emerging Technologies 19 (2013) 29–43 Contents lists available at SciVerse ScienceDirect Innovative Food Science and Emerging Technologies j ournal homepage: www. /locate/ifse t Nanostructured lipid carriers (NLC): A potential delivery system for bioactive food molecules Fardin Tamjidi a,⁎, Mohammad Shahedi a, 1, Jaleh Varshosaz b, 1, Ali Nasirpour a a Department of Food Science and Technology-Center of Excellence for Safety and Quality of Foods, College of Agriculture, Isfahan University of Technology, Isfahan 84156-83111, Iran b Department of Pharmaceutics, Faculty of Pharmacy and Novel Drug Delivery Systems Research Center, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran a r t i c l e i n f o a b s t r a c t Article history: Particle size and physical state of the lipid phase are major factors influencing the permanence of lipid disper- Received 11 November 2012 sions. Nanostructured lipid carriers (NLC) are a delivery system in which partial-crystallized lipid particles Accepted 17 March 2013 with mean radii ≤ 100 nm are dispersed in an aqueous phase containing emulsifier(s), as a potential delivery system may have some advantages in certain circumstances when compared with other colloidal carriers. NLC Editor Proof Receive Date 17 April 2013 are a useful nutraceutical delivery system with high drug loading, encapsu