探讨药物治疗联合饮食控制治疗溃疡性结肠炎的临床效果观察.docVIP

精品论文 参考文献 探讨药物治疗联合饮食控制治疗溃疡性结肠炎的临床效果观察 黑龙江省嫩江县伊拉哈镇中心卫生院 161437 　　【摘 要】目的 研究并观察溃疡性结肠炎患者采用药物治疗联合饮食控制治疗的临床疗效及其安全性。方法 此次研究的对象是选取该院2013年9月—2014年6月收治的68例溃疡性结肠炎患者。将其临床资料进行回顾性分析，并按照就诊顺序随机分为实验组（采用美莎拉嗪联合饮食控制治疗）和对照组（单纯给予美莎拉嗪治疗），对比观察两组患者临床疗效。结果 实验组治疗总有效率（91.1%）明显高于对照组（73.5%），差异有统计学意义（Plt;0.05）；两组患者治疗后CRP及IL-8指标水平较治疗前均有明显降低，差异有统计学意义（Plt;0.05），而IL-10指标水平较治疗前明显升高（Plt;0.05），但是两组间对比，实验组改善程度更为显著，差异有统计学意义（Plt;0.05）。且实验组患者不良反应发生率（11.8%）明显低于对照组（29.4%），差异有统计学意义（Plt;0.05）。结论 溃疡性结肠炎患者采用美莎拉嗪联合饮食控制治疗的临床效果显著，值得在临床上进一步推广。 　【关键词】溃疡性结肠炎；美莎拉嗪；饮食控制；临床疗效 　　[Abstract] Objective To investigate the clinical efficacy and safety of drug therapy combined with diet therapy in patients with ulcerative colitis. Methods the study was conducted in 68 patients with ulcerative colitis treated in our hospital from June 2014 to September 2013. The clinical data were retrospectively analyzed，and randomly divided into experimental group（using the beauty of Sarah in the combination of diet control and treatment）and control group（treated with combination therapy，Sarah）were observed and compared between the two groups of patients with clinical curative effect. Results treatment group total effective rate（91.1%）was significantly higher than the control group（73.5%），the difference was statistically significant（Plt;0.05）；the two groups of patients after treatment of CRP and IL-8 levels were decreased，the difference was statistically significant（Plt;0.05），and the IL-10 index was significantly higher than that before treatment（Plt;0.05）. But the contrast between the two groups，the experimental group improved more significantly，the difference was statistically significant（Plt;0.05）. And the incidence of adverse reaction in the experimental group（11.8%）was significantly lower than that of the control group（29.4%），the difference was statistically significant（Plt;0.05）. Conclusion the clinical effect of the treatment of patients with ulcerative colitis with the combination of Sarah and the United States is significant，which