消化性溃疡英文.ppt

Canceration癌变 (Gastric ulcer ) Questions for summary: (1) What does Peptic Ulcer Disease refer to? (2) What are the symptoms and signs you can find in the patients with peptic ulcer disease? (3) Which kind of complication most frequently occur? THANK YOU! Peptic Ulcer Disease消化性溃疡病 Question: What’s the meaning of “Peptic Ulcer Disease”? Definition Peptic Ulcer Disease is defined as an ulcer occurring in a region that touches gastric acid(胃酸) and pepsin(胃蛋白酶) and usually refers to gastric ulcer(胃溃疡) or duodenal ulcer(十二指肠溃疡). Typical endoscopic appearance of a benign gastric ulcer. The ulcer is on the angularis, the most common location for a gastric ulcer, and is well circumscribed without any associated mass effect. The surrounding mucosa is mildly erythematous红斑的 and without nodularity结节. Typical radiographic features of a benign gastric ulcer. A large well-circumscribed ulcer is seen on the angularis. a posterior duodenal ulcer Typical radiographic features of duodenal ulcer. This duodenal bulb ulcer is associated with marked edema, resulting in the appearance of radiating folds to the ulcer crater. The bulb is also distored secondary to previously existing ulceration. Questions: What does ulcer 溃疡 mean? How can we differentiate between ulcer and erosion 糜烂? Erosions in the duodenal bulb and a posterior duodenal ulcer Erosion糜烂 : a superficial lesion caused by denudation of the surface epithelium（上皮细胞） ulcer 溃疡: a mucosal defect extending into the muscularis mucosa(粘膜肌层) Mucosa can be divided into: Epithelium 上皮 Lamina propria 固有层 Muscularis mucosae 粘膜肌层 Clinical manifestations of Peptic Ulcer Diseases消化性溃疡病的临床表现 symptoms 症状 abdominal pain 腹痛 located in the epigastric(上腹) area; burning in quality(烧灼样); occurred on an empty stomach 2 to 4 hours after meals and/or at night (nocturnal pain夜间疼痛); relieved by antacids(抗酸剂) and/or meals(进餐); tend to wax and wane(加重与缓解) over months