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窗体顶端
Nature
? 2000 Nature Publishing Group
Volume 406(6797)? ? ? ? ? ? ?17 August 2000? ? ? ? ? ? ?pp 747-752
Molecular portraits of human breast tumours
[Letters to Nature]
Perou, Charles M.*?; S?rlie, Therese??; Eisen, Michael B.*; van de Rijn, Matt§; Jeffrey, Stefanie S.[//]; Rees, Christian A.*; Pollack, Jonathan R.[curved stem paragraph sign ornament]; Ross, Douglas T.[curved stem paragraph sign ornament]; Johnsen, Hilde?; Akslen, Lars A.#; Fluge, ?ystein[white star]; Pergamenschikov, Alexander*; Williams, Cheryl*; Zhu, Shirley X.§; L?nning, Per E.**; B?rresen-Dale, Anne-Lise?; Brown, Patrick O.[curved stem paragraph sign ornament]??; Botstein, David*
* Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA
? Department of Genetics, The Norwegian Radium Hospital, N-0310 Montebello Oslo, Norway
§ Department of Pathology, Stanford University School of Medicine, Stanford, California 94305, USA
[//] Department of Surgery, Stanford University School of Medicine, Stanford, California 94305, USA
[curved stem paragraph sign ornament] Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, USA
# Department of Pathology, The Gade Institute, Haukeland University Hospital, N-5021 Bergen, Norway
[white star] Department of Molecular Biology, University of Bergen, N-5020 Bergen, Norway
** Department of Oncology, Haukeland University Hospital, N-5021 Bergen, Norway
?? Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, California 94305, USA
?These authors contributed equally to this work
Received 7 February; accepted 25 May 2000.
Correspondence and requests for materials should be addressed to D.B.
(e-mail: botstein@) or P.O.B.
(e-mail: pbrown@).
Outline
Abstract
Methods
Acknowledgements
Graphics
Figure 1
Figure 2
Figure 3
Abstract
Human breast tumours are diverse in their natural history and in their responsiveness to treatments 1. Variation in transcriptional prog
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