psa灰区患者术前检查与其前列腺穿刺阳性情况的相关性分析.docVIP

PSA灰区患者术前检查与其前列腺穿刺阳性情况的相关性分析 　　[摘要]目的 研究前列腺特??性抗原（PSA）灰区患者术前检查与其前列腺穿刺阳性情况的相关性。方法 回顾性研究2011年3月～2016年3月在沐阳县中心医院泌尿外科和徐州市中心医院泌尿外科就诊的处于PSA灰区进行前列腺穿刺活检检查的495例患者，根据穿刺结果将其分为穿刺阳性组（n=150）和穿刺阴性组（n=345），比较两组年龄、是否吸烟、是否高血压、是否有糖尿病、MRI结节、直肠指检（DRE）结节、PSA、游离PSA（FPSA）、PSA密度（PSAD）、前列腺体积等情况，并对其穿刺阳性结果与术前检查的相关性进行分析。结果 两组患者在年龄、是否吸烟、是否高血压、是否有糖尿病及FPSA、前列腺体积上比较，差异无统计学意义（P=0.1078、0.6375、0.0517、0.4811、0.1363、0.2915，均P0.05），而在MRI结节、DRE结节、PSA、PSAD上比较，差异均有统计学意义（均P 　　[关键词]前列腺特异性抗原；灰区；经直肠前列腺穿刺活检术；前列腺癌 　　[中图分类号] R446.8 [文献标识码] A [文章编号] 1674-4721（2016）12（c）-0048-03 　　Relationship of prostate biopsy positive results and preoperative examination in prostate specific antigen gray area patients 　　WANG Mei-cai1 ZHOU Rong-sheng2 ZHOU Xiang-ju2 PANG Kun2 HAN Cong-hui2 　　1.Department of Urology，Central Hospital of Shuyang County in Jiangsu Province，Shuyang 223600，China；2.Department of Urology，Xuzhou City Central Hospital Affiliated to Southeast University in Jiangsu Province，Xuzhou 221000，China. 　　[Abstract]Objective To investigate correlation of prostate biopsy positive results and preoperative examination in prostate specific antigen （PSA） Gray area patients.Methods 495 patients who underwent prostatic biopsy in the PSA gray area from March 2011 to March 2016 in Department of Urology of Central Hospital of Shuyang County and Xuzhou City Central Hospital were retrospectively studied and divided into two groups of prostatic biopsy positive group （n=150） and prostatic biopsy negative group （n=345） according to the results of prostatic biopsy.Age，smoking or not，whether hypertension，whether diabetes，MRI nodules，digital rectal examination （DRE） nodules，PSA，free PSA （FPSA），PSA density （PSAD），prostate volume between two groups were compared，and correlation of puncture positive result and preoperative examination was analyzed.Results There were no significant differences between two groups in age，smoking or not，whether hypertension，whether diabetes，and FPSA，prostate volume between two groups （P=0.1078，0.6375，0