固尔苏对生命的尊重科室会PPT.ppt

固尔苏?显著缩短机械通气时间 固尔苏?(100mg/kg或200mg/kg)与Beractant(100mg/kg)相比 固尔苏?(100mg/kg)与Beractant(100mg/kg)相比 Meta分析: 与Beractant比较，固尔苏?组的机械通气时间显著缩短 有利于固尔苏? 有利于Beractant 加权均数差（95%CI） Singh N, Hawley KL, Viswanathan K. Efficacy of porcine versus bovine surfactants for preterm newborns with respiratory distress syndrome: systematic review and meta-analysis. Pediatrics. 2011 Dec;128(6):e1588-95. 固尔苏?相比同类药物显著缩短CPAP时间 赵冰,潘家华.不同肺表面活性物质治疗新生儿呼吸窘迫综合征疗效比较.中国新生儿科杂志.2014; 29(3):158-161. 固尔苏?与珂立苏组CPAP时间的比较 P＜0.05 n=36 n=32 *CPAP: Continuous Positive Airway Pressure, 持续气道正压通气 固尔苏?显著缩短气管插管时间 Gharehbaghi MM, Sakha SH, Ghojazadeh M, et al. Complications among premature neonates treated with beractant and poractant alfa. Indian J Pediatr. 2010 Jul;77(7):751-4. 固尔苏?与Survanta组气管插管时间的比较 P=0.05 n=79 n=71 固尔苏?比Beractant组拔管率高 Fujii AM,?Patel SM,?Allen R，et al. Poractant alfa?and?beractant?treatment?of very?premature infants?with?respiratory distress syndrome. J Perinatol.?2010 Oct;30(10):665-70. Dizdar EA, Sari FN, Aydemir C, et al. A randomized, controlled trial of poractant alfa versus beractant in the treatment of preterm infants with respiratory distress syndrome. Am J Perinatol. 2012 Feb;29(2):95-100. P＜0.05 固尔苏与Beractant治疗后3天内拔管率的比较 P=0.027 P=0.029 固尔苏与Beractant治疗后48h、72h拔管率的比较 固尔苏?比Beractant组重复给药率显著降低 Singh N, Hawley KL, Viswanathan K. Efficacy of porcine versus bovine surfactants for preterm newborns with respiratory distress syndrome: systematic review and meta-analysis. Pediatrics. 2011 Dec;128(6):e1588-95. 固尔苏?(100mg/kg或200mg/kg) VS Beractant 100mg/kg 固尔苏? 200mg/kg VS Beractant 100mg/kg 固尔苏? 100mg/kg VS Beractant 100mg/kg P＜0.05 P＜0.05 NS 固尔苏? ，固尔苏? 200mg/kg，固尔苏? 100mg/kg与Beractant组重复给药率的比较 固尔苏?比Beractant组所需重复剂量显著减少 Dizdar EA, Sari FN, Aydemir C, et al. A randomized, controlled trial of poractant alfa versus beractant in the treatment of preterm infants with respiratory distress syndrome. Am J Perinatol. 2012 Feb;29(2):95-100. 固尔苏?与Beractant组需要≥2剂的患儿比例的比较 P=0.023 n=61 n=65 固尔苏?显著降