[医学]Metabolism and Temperature.ppt

Energy Metabolism ＆ Body Temperature General consideration 1.A review of principal chemical processes of the cell; 2.An analysis of their physiologic implications, especially the manner in which they fit into the overall concept of homeostasis. Concept of energy metabolism： The processes of liberation, transformation, storage and utilization of the energy produced by the material metabolism in the body . Source,transfer and storage of energy 1)Adenosine triphosphate (ATP) functions as an “energy currency” in metabolism. 2)CP (phosphocreatine) functions as an accessory storage depot for energy and as an “ATP buffer” Concept of “free energy” The energy in foods can be made by the chemical reactions in the cells The energy is available to the various physiologic systems of the cells . The amount of energy liberated by completed oxidation of a food is called the free energy of oxidation of the food . Represented by the symbol ΔG. Role of “Adenosine Triphosphate (ATP )” in metabolism ATP is an essential link between energy-utilizing and energy-producing functions of the body.---the energy currency of the body. Energy derived from the oxidation of food is used to convert adenosine diphosphate (ADP) to ATP. ATP is then consumed by the various reactions of the body . Metabolic rate The metabolism of the body simply means all the chemical reactions in all the cells of the body. Metabolic rate is normally expressed in terms of the rate of heat liberation during chemical reactions. Heat is the end product of almost all the energy released in the body. Measurement of the whole-body metabolic rate Direct Calorimetry——?? to measure the sum of heat production of whole body in a unit of time physically difficult to perform used only for research purposes Basal Metabolic Rate (BMR)－－ ??? The metabolism so measured includes the fundamental basal metabolism of all cells and some steady functions such as those of the k