立体定向微创血肿清除术治疗少量丘脑出血.doc

立体定向血肿清除术治疗出血的临床研究 尹恝，周亮，吕田明，潘速跃姬仲，刘晓加南方医科大学南方医院神经内科，广东广州，510515139.com。 摘要目的分析立体定向血肿清除术微创血肿术治疗出血的。方法出血量~107.9 mL的出血患者例，立体定向组0例，组1例。立体定向组行立体定向血肿清除术常规微创血肿术术12 h后给予尿激酶1u血肿腔保留2~4 h后冲洗引流疗。患者治疗前及治疗后14 d和30 dNIHSS评分和治疗后30 d的GOS-E评分并进行统计分析。结果立体定向组14 d和30 d的NIHSS显著于组 d的GOS-E评分值显著高于组P 0.01），表明立体定向血肿清除术后患者。结论立体定向血肿清除术患者。关键词立体定向微创清除术脑出血 中图法分类号： R651.1 文献标识码：A Clinical study of the stereotactic evacuation therapy on putaminal hemorrhage YIN Jia, ZHOU Liang, LüTian-Ming, PAN Su-Yue, JI Zhong, LIU Xiao-Jia, ZHENG Wei, ZHU Jia-Jia Department of Neurology, Nangfang Hospital, Southern Medical University, Guangzhou 501515, China Abstract：Objective To compare the healing effects of the stereotactic evacuation therapy and the minimally traumatic puncture drainage therapy on the putaminal hemorrhage. Methods Thirty-nine patients with putaminal hemorrhage, which hematoma volume was between 16.0 to 107.9 mL, were divided into two groups: the stereotactic evacuation therapy group (n= 20) and the minimally traumatic therapy group (n = 19). The patients in the stereotactic evacuation therapy group had received stereotactic evacuation therapy, and the patients in the minimally traumatic therapy group had received the minimally traumatic puncture drainage therapy. Urokinase of 10 to 20 ku was administered into the hematoma repeatedly12 hours after the operation and retained for 2 to 4 hours for eliminating the hematoma completely. Allopathy was administered to each patient. Neurologic impairment degree scores were assessed by National Institutes of Health Stroke Scale (NIHSS) at the day before treatment, 14 and 30 days after treatment separately. The Glasgow Outcome Score- Extended (GOS-E) were assessed 30 days after treatment for comparing the outcome between the two groups. Results Both of the NIHSS scores in the stereotactic evacuation therapy group after 14 days or 30 days’ treatment were significantly lower than that of the minimally traumatic therapy group; The GOS-E