单能量对双源双能量CT心肌灌注成像中线束硬化.doc

DOI：10.16016/j.1000-5404.201411236 双源双能量CT心肌灌注扫描的单能量成像对线束硬化伪影的校正研究 魏 淼，王思杭，温家华，刘 洋，吕发金 （400016重庆，重庆医科大学附属第一医院放射科） 【摘要】目的 观察双能量CT心肌灌注成像中线束硬化伪影（beam-hardening,BH）的好发部位，比较不同单能量成像对线束硬化伪影的校正效果和图像质量。方法 对84例需行心脏CT增强检查的拟诊或确诊冠心病患者进行双源双能量CT（100/Sn140kVp）P0.05）；左心室的基底段伪影最明显（36.5%，100/274），其次为间隔壁（25.91%）、上腔静脉旁段（24.82%）、后壁（12.77%）（P0.05）；心肌伪影区碘含量（-2.37±0.84）mgI/g低于非伪影区碘含量（3.5±0.92）mgI/g（t=-19.36,P0.001）；85keV的非伪影心肌CT值（93.52±18.52）HU与120kV（96.06±16.32）HU最接近，CT值的组间差异有统计学意义（P0.01）；85keV的SD最小[（12.98±3.16），P0.01]，非伪影心肌的SNR: 75keV（6.89±1.79）与85keV（6.5±1.7）较高，二者无明显差别（t=1.5,P=0.14），CNR: 75keV最高[（18.79±6.76），P0.001]，85keV（15.4±5.67）与65keV（15.53±4.56）之间无明显差别（t=-0.27, P =0.79）；图像质量评分：85keV最高,两名诊断医生对六组图像进行评分一致性高度一致（Kappa=0.79,P0.001）。结论：左心室的基底段、间隔壁和上腔静脉旁易出现线束硬化伪影；正常心肌密度在85keV与混合能量120kV最接近，85keV能在最有效纠正线束硬化伪影的同时保证较好的图像质量。 【关键词】双源双能量CT心肌灌注扫描；单能量成像；线束硬化伪影；图像质量 【中图分类号】R814.42 【文献标志码】The study of Beam-hardening correction for monochromatic imaging via dual-energy myocardial perfusing imaging with dual-source CT Wei Miao Wang Sihang Wen Jiahua Liu Yang LV Fajin（Department of Radiology the First Affiliated Hospital of Chongqing Medical University,Chongqing China,400016） 【Abstract】Objective:To observe the high incidence site of beam-hardening artifacts in dual-energy CT myocardial perfusing imaging,and compare the image quality and effcet for beam-hardening correcting of different monochromatic energe images via dual-energy myocardial perfusing imaging with dual-source CT.Methods: 84 patients requiring cardiac enhancement-CT examination were underwent dual-energy （100/Sn140kVp）myocardial perfusing imaging with dual-source CT ,who were suspected or definited coronary artery disease enrolled.Apllicating specialized post-processing software with results of iodine maps and.monoenergetic images under 65keV,75keV,85keV,95keV,105keV.To count the number of beam-hardening artifacts with control of M image（weighted Polychromatic 120kV）which is automated system generation. Comprehensive