Patato bile acid rat土豆.pdf

NutritionResearch,Fbl. 17.Nos. 11/12,pp. 1671-1682.1997 Copyright0 1997ElsevimScienceInc. PrintedintheUSA. AUrightsresewed 0271~5317/97$17.00 + .oo EL.SEVIER PII s0271-5317(97)00174-7 EFFECTS OF RESISTANT POTATO STARCH ON CHOLESTEROL AND BILE ACID METABOLISM IN THE RAT JoCarol Chezem, Ph.D., R.D., Emily Furumoto, Ph.D., and Jon Story, Ph.D. Department of Foods and Nutrition, Purdue University, West Lafayette, IN ABSTRACT This study examines the effects of two types of resistant starch (RS),raw starch from uncooked potatoes and retrograded starch in the form of cooked and cooled potatoes, on cholesterol and bile acid metabolism in rats. Groups of 8 male Wistar rats were fed a semipurified diet containing 15% cellulose, freeze-dried raw potatoes, or freeze-dried cooked potatoes for four weeks. Serum cholesterol, liver cholesterol, and fecal steroid excretion were determined. Serum cholesterol was significantly higher and liver cholesterol was significantly lower in response to the cooked potato diet compared to the cellulose or raw potato diet. Total steroid excretion was significantlyhigher in rats fed the cooked potato diet (26.31mg/d) compared to those fed the cellulose or raw potato diet (14.27mg/d and 16.81 mg/d, respectively). Daily total bile acid excretion was significantly