慢性肾衰竭与常生活.ppt

* Ischemia-reperfusion injury is an important cause of organ damage in diverse clinical circumstances such as early allograft dysfunction after organ transplantation.) When one markedly reduces or produces cessation of blood flow (i.e., induces ischaemia) to a vascular bed and then rapidly reperfuses that vascular bed (i.e., reestablishes blood flow), a severe perturbation occurs to the organ perfused by that vascular bed. This phenomenon is known as reperfusion injury or Ischaemia-reperfusion injury (IRI). * Ischemia-reperfusion injury is an important cause of organ damage in diverse clinical circumstances such as early allograft dysfunction after organ transplantation.) When one markedly reduces or produces cessation of blood flow (i.e., induces ischaemia) to a vascular bed and then rapidly reperfuses that vascular bed (i.e., reestablishes blood flow), a severe perturbation occurs to the organ perfused by that vascular bed. This phenomenon is known as reperfusion injury or Ischaemia-reperfusion injury (IRI). * Ischemia-reperfusion injury is an important cause of organ damage in diverse clinical circumstances such as early allograft dysfunction after organ transplantation.) When one markedly reduces or produces cessation of blood flow (i.e., induces ischaemia) to a vascular bed and then rapidly reperfuses that vascular bed (i.e., reestablishes blood flow), a severe perturbation occurs to the organ perfused by that vascular bed. This phenomenon is known as reperfusion injury or Ischaemia-reperfusion injury (IRI). * Ischemia-reperfusion injury is an important cause of organ damage in diverse clinical circumstances such as early allograft dysfunction after organ transplantation.) When one markedly reduces or produces cessation of blood flow (i.e., induces ischaemia) to a vascular bed and then rapidly reperfuses that vascular bed (i.e., reestablishes blood flow), a severe perturbation occurs to the organ perfused by that vascular bed. This phenomenon is known as reperf