LECTURE1-生物信息学教学计划与绪论X.pptx

何淼 Miao HE Ph.D Associate Professor Department of Biology, Sun Yat-sen University 135 West Xingang Road, Guangzhou Guangdong 510275 Tel. : 020-8403 4771,e-mail: mmh168168@ Office hours: by appointment (send email) ;自我介绍 ? 课程安排 ? 灰质脊髓炎问题 ? 什么是生物信息学 ? 生物信息学历史 ? 生物信息学资源 ? 生物信息学职业;课程描述 ? This course will provide a broad introduction to the area of bioinformatics. Topics include: biology overview, databases, the alignment problem, proteins and protein structure-function, introductory phylogenetics, use of public databases，and some basic algorithm. ?;主要教学内容简介;Course outline;Course outline;Course schedule;教学进程安排;Course schedule;基于任务的学习;参考书目推介;参考书目推介;The Poliovirus Problem;The Poliovirus Problem;The Poliovirus Problem;自我介绍 ? 课程安排 ? 灰质脊髓炎问题 ? 什么是生物信息学 ? 生物信息学历史 ? 生物信息学资源 ? 生物信息学职业;What is Bioinformatics?;What is Bioinformatics?;What is Bioinformatics?;Bioinformatics Definition;Bioinformatics (S.M. Brown, 2000) ? Bioinformatics can be defined as the use of computers for the acquisition, management, and analysis of biological information. It exists at the intersection of molecular biology, computational biology, clinical medicine, database computing, the Internet, and sequence analysis. ;Weizmann Institute of Science ? … although the term ‘Bioinformatics’ is not really well-defined, you could say that this scientific field deals with the computational management of all kinds of biological information, whether it may be about genes and their products, whole organisms or even ecological systems. ;National Institutes of Health (NIH) ? Research, development, or application of computational tools and approaches for expanding the use of biological, medical, behavioral or health data, including those to acquire, store, organize, archive, analyze, or visualize such data.;它是采用信息科学、计算机科学、数学、物理学、化学、比较生物学等学科的观点和方法对生命的现象及其组成分子（核酸、蛋白等）进行研究的新兴学科。 主要任务是收集、储存、分发基因组的数据和信息，管理和分析、处理基因组及相关的蛋白质、mRNA的信息。根据基因组数???和信息的比较分析，发现新的基因，并对基因结构和功能进行研究。;What is Bioinformatics?;History o