enhancement of essential amino acid contents in crops by genetic engineering and protein design - beauregard推荐.pdf

Plant Biotechnology Journal (2006) 4, pp. 561–574 doi: 10.1111/j.1467-7652.2006.00204.x Marc Beauregard and Mary A. HeffordOriginal ArticleEngineering nutritive crops 2© 2006 Blackwell Publishing LtdOxford, UK1467-7644? 2006?Blackwell Publishing LtdPBIPlant Biotechnology Journal Enhancement of essential amino acid contents in crops by genetic engineering and protein design 1, 2 Marc Beauregard * and Mary Alice Hefford 1Plant Biology Group, Département de Chimie-Biologie, Université du Québec à Trois-Rivières, Trois-Rivières, QC, Canada, G9A 5H7 2Centre for Biologics Research, Biologics and Genetic Therapies Directorate, A/L:2201C, Health Canada, Ottawa, ON, Canada, K1A 0L2 Received 28 February 2006; Summary revised 1 May 2006; The importance and urgency of providing humans and animals with quality proteins are accepted 5 May 2006. *Correspondence (fax (819) 376-5084; reflected in the growing scientific and industrial interest in augmenting the nutritive e-mail marc.beauregard@uqtr.ca) value of the world’s protein sources. Such nutritive value is determined by the protein content in ‘essential amino acids’, those that cannot be synthesized de novo and that Keywords: animal feeding, nutritive proteins, plant biotechnology, protein must be supplied from the diet. It is the object of this review to discuss recent advances design, protein stability, seed storage in the genetic modification of crops that aim to provide enhanced quantities of proteins. essential amino acids.