msm和fkbi对冠状动脉分叉病变介入疗效的影响.doc

msM和FKBI对冠状动脉分叉病变介入疗效的影响 胡静雯，葛雷，葛均波2 [摘要] 目的 评估msM后扩张技术的临床可行性；比较msM和最终对吻球囊扩张（final kissing balloon inflation，FKBI）intravenous ultrasound，main adverse cardiac events，MACE)发生率和支架内血栓发生率。结果 msM组患者48名，FKBI组患者54名。FKBI组分支血管管径即刻获得明显优于msM组（p=0.004）；主支血管管径即刻获得FKBI、msM两组间无显著差异（p0.05）。msM组的主支血管支架膨胀指数和支架对称指数明显优于FKBI组（p=0.04；p0.001）。两组患者住院和临床随访期间MACE发生率无统计学差异（p0.05）。结论 msM技术使主支血管支架近端的对称指数和膨胀指数优于FKBI技术，但其对临床效果的影响仍需进一步长期、大规模临床研究。 [关键词] 分叉病变；介入治疗；药物洗脱支架；最终对吻球囊扩张 Comparison of the Mid-term Clinical and Angiographic Outcomes of msM and FKBI in the Treatment of Coronary Bifurcation Lesions HU Jingwen GE Lei GE Junbo （Department of cardiology, Jiangsu Province Hospital, Nanjing, 210029, China; Department of cardiology, Zhongshan Hospital, Shanghai, 200032, China） Corresponding author：Ge Junbo, E-mail：ge.junbo@ [Abstract] Objective To evaluate the safety and efficacy of msM and compare the clinical results of this new post-dilation strategy with FKBI in treating coronary bifurcation lesions. Methods A total of 102 patients with bifurcation lesions were enrolled. Angiographic results, IVUS results and the incidence of MACE of patients between msM group and FKBI group were compared respectively. Results msM was performed in 48 patients and FKBI in 54 patients. Acute lumen gain of side branch in FKBI group was larger than that in msM group (p=0.004). Stent symmetry index (SSI) and stent expansion index (SEI) of main branch in msM group was larger than that in FKBI group (p=0.04; p0.001). There was no statistic difference in the incdence of in-hospital MACE and mid-term MACE between the two groups (p0.05). Conclusions The msM strategy is a promising post-dilation method which has better IVUS results than FKBI with similar mid-term angiographic and clinical outcomes. Larger scale randomized study with long-term follow up is necessary. [Key words] coronary bifurcation lesions; percutaneous coronary intervention; drug eluting stent; final kissing balloon inflation 在经皮冠状动脉介入治疗（percutaneous co