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牛津英语词典生物化学与分子生物学
194
edeine EF-1
graded, the dose that produces 50% of the maximal response ApoB, several glirtamate receptor mRN As. and Wilms tumour sus-
to that drug or agent . ceptible gene mRNA . In the case of ApoB , a cytidine residue is
edeine any of several pentapeptide-amide antibiotics deaminated to a uridine residue so that the codon for gluta-
elaborated by a strain of Bacillus brevis and effective against mine (CAA) becomes a stop codon (UAA) ; hence, translation
Gram-positive and Gram-negative bacteria, some fungi and results in a shortened form of the protein .
other eukaryotic cells, and some neoplastic cells . Edeine AI , editosome a macromolecular complex involved in the editing
Na](N-{A^-[N-(B-tyrosyl)isoseryl]-2,3-diaminopropionyl}-2,6- of RNA transcripts . Specific ribonucleotide complexes include
a
diamino-7-hydroxyazela-9-yl)glycyl]spermidine, and its N - guide RNA (see gRNA), which specifies the edited sequence.
amidinospermidine analogue , edeine B1, are highly active ; Edman degradation a procedure used in sequencing
their respective constitutional isomers, edeines Aa and B , (poly)peptides in which amino-acid residues are removed
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