药剂学英文版chapter 1.ppt

1 Concepts and tasks A concepts (1) drug It is defined as an agent intended for use in the diagnosis, mitigation, treatment, cure, or prevention of disease in humans or in other animals. (2) pharmaceutics basic theory formulation design drug product preparation techniques quality evaluation correct application (3) dosage forms forms of administration e.g. tablet, capsule, injection, granule… (abstract) (4) pharmaceutical preparations drug+form e.g. aspirin tablets, 0.5% glucose infusion… (objective) (5) pharmaceutical manufacturing the process of research and preparation of drug product (verb.) (6) drug delivery systems (DDS) modern dosage forms e.g. sustained or controlled; targeting; transdermal; solid dispersion; liposomes; microencapsulation… B Tasks to prepare safe, effective, stable and convenient pharmaceutical preparations (1) basic theory (2) dosage forms(esp. Chinese traditional medicine and biomedicine) new preparation techniques excipients equipment(sealed, effective, multifunction, automation and continuity) 2 Branches industrial P.—essential physical P. biopharmaceutics pharmacokinetics basic P. polymers in P. clinical P. hospital P. dispensing P. 3 Dosage forms A Importance (1)Change the applicative properties of drug (2)Adjust effective time (3)Decrease the side effects of drug (4)Improve targeting ability (5)Affect effectiveness B Types (1)According to administration routes gastrointestinal tract (GIT): oral injection (IM, IV, SC…) inhale parenteral transdermal transmucous membrane (buccal, sublingual…) cavity (rectal, ear, nose,