抗生素英文课件精品 Health Care Assiciated Infections and Antibiotic Resistance an increasing threat to Patient Safety in Europe.ppt

抗生素英文课件精品 Health Care Assiciated Infections and Antibiotic Resistance an increasing threat to Patient Safety in Europe.ppt

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抗生素英文课件精品 Health Care Assiciated Infections and Antibiotic Resistance an increasing threat to Patient Safety in Europe

* * Risk factors External/none host Catheters and other invasive devices Surgeries Invasive procedures Antibiotic exposure Inadequate staff and overcrowding Internal/Host Extremes of age Immune status Illness severity Comorbidities Colonization status New challenges http://ecdc.europa.eu/en/publications/Publications/Forms/ECDC_DispForm.aspx?ID=740 Challenges in developing Case-Definitions for HAI Assumptions: 48 or 72 hours after admission Not incubating at the time of admission Can manifest after discharge Acquired in healthcare setting Use both clinical and lab criteria Examples of potential for misclassification Case 1 80 y.o. patient, multiple medical problems, lives at home, visited by grandchildren who have colds 2 days later, admitted for hip fracture 4 days after admission she develops RSV (respiratory syncytial virus) pneumonia What you think? Examples of potential for misclassification Case 2 55 y.o. patient, admitted for work-up and management of chest pain, cared for by healthcare worker taking care of another patient who has MRSA Discharged after 2 days in hospital Develops an MRSA soft tissue infection 3 weeks later while in the community What now??? Incubation periods C.difficile unknown MRSA unknown VRE unknown Influenza 1-4 days RSV 2-8 days Norovirus 24-48 hours Conclusions There are always outbreaks going on at the hospitals. However they might not be detectable Hospitals are a suitable place for outbreak investigation It is not always easy to define the cases Outbreaks agents circulating frequently. Therefore you need good microbiological evidence to confirm your cases. Hands are the most common public transport of microorganisms * 18 November 2010 Story of glory the first antibiotic used successfully to treat people with serious infectious diseases - begins with a bit of luck. Alexander Fleming, a British scientist, noticed in 1928 that mould had prevented the growth of bacteria in his lab. But th

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