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受体结合位点只有-Epizone
Influenza Viruses: from Epidemiology to
Host Jump
George F Gao (高福)DPhil
China CDC
Institute of Microbiology, Chinese Academy of Sciences
gaof@
Influenza Viruses: Emerging and Re-emerging
Re-emerging: Seasonal flu every year
Emerging: Avian flu and Pandemics
News in the Media
News in the Media
Always Keep An Eye On
1. Epidemiology and Surveillance
2. Host Jump—Interspecies Transmission
Pandemics and epidemics of influenza viruses
H7N9
2013
Nature Volume: 480,Pages:S2-S3 Date published:(08 December 2011)
Natural Cycle of the Influenza viruses
Ecology of Ebola:
Batmammalshuman
Natural Human-to-
Intermediate Human
Hosts/Reservoir human
Hosts Infections
Hosts transmission
MERS-CoV life cycle to infect humans
Bat
Humans
Henipahvirus
Horse
Bat
Human
Why do we have so many emerging viruses?
……--SARS--Bird flu—MERS—Ebola—Zika--…….
Climate and ecological changes
But the polar bear or
penguin might not be the
only threatened species “How it threatens
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