红树林来源streptomyces sp.ouc6819中多烯大环内酯类抗生素的生物合成研究-study on biosynthesis of polyene macrolide antibiotics from mangrove sp. ouc 6819.docx
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红树林来源streptomyces sp.ouc6819中多烯大环内酯类抗生素的生物合成研究-study on biosynthesis of polyene macrolide antibiotics from mangrove sp. ouc 6819
目录1 前言................................................................................................. 11.1 研究背景.............................................................................................................11.2 海洋放线菌研究的历史..................................................................................... 21.3 海洋放线菌的分布和分类..................................................................................31.4 海洋放线菌来源的次级代谢产物...................................................................... 41.5 多烯大环内酯类化合物..................................................................................... 41.5.1 多烯大环内酯类化合物的生物活性与研究进展............................................. 41.5.2 多烯大环内酯类化合物的生物合成................................................................ 51.5.3 多烯大环内酯类化合物的组合生物合成.........................................................91.6 本研究的目的和意义......................................................................................... 9Streptomyces sp.OUC6819 最适生长条件的摸索112.1 引言................................................................................................................... 112.2 实验材料...........................................................................................................112.2.1 菌株.................................................................................................................112.2.2 实验仪器......................................................................................................... 112.2.3 培养基.............................................................................................................122.2.4 抗生素及其使用浓度..................................................................................... 132.3 实验方法............................................................................................................142.3.1 Streptomyces sp.OUC6819 最适培养条件的摸索142.3.2 抗生素敏感实验............................................................................................. 142.3.3 Streptomyce
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