急性等容血液稀释对兔脑缺血再灌注神经细胞凋亡 s-100β蛋白及炎症因子的影响-effects of acute normovolemic hemodilution on apoptosis s - 100β protein and inflammatory factors in rabbit cerebral ischemia-reperfusion neurons.docxVIP
- 1、本文档共39页,可阅读全部内容。
- 2、有哪些信誉好的足球投注网站(book118)网站文档一经付费(服务费),不意味着购买了该文档的版权,仅供个人/单位学习、研究之用,不得用于商业用途,未经授权,严禁复制、发行、汇编、翻译或者网络传播等,侵权必究。
- 3、本站所有内容均由合作方或网友上传,本站不对文档的完整性、权威性及其观点立场正确性做任何保证或承诺!文档内容仅供研究参考,付费前请自行鉴别。如您付费,意味着您自己接受本站规则且自行承担风险,本站不退款、不进行额外附加服务;查看《如何避免下载的几个坑》。如果您已付费下载过本站文档,您可以点击 这里二次下载。
- 4、如文档侵犯商业秘密、侵犯著作权、侵犯人身权等,请点击“版权申诉”(推荐),也可以打举报电话:400-050-0827(电话支持时间:9:00-18:30)。
- 5、该文档为VIP文档,如果想要下载,成为VIP会员后,下载免费。
- 6、成为VIP后,下载本文档将扣除1次下载权益。下载后,不支持退款、换文档。如有疑问请联系我们。
- 7、成为VIP后,您将拥有八大权益,权益包括:VIP文档下载权益、阅读免打扰、文档格式转换、高级专利检索、专属身份标志、高级客服、多端互通、版权登记。
- 8、VIP文档为合作方或网友上传,每下载1次, 网站将根据用户上传文档的质量评分、类型等,对文档贡献者给予高额补贴、流量扶持。如果你也想贡献VIP文档。上传文档
查看更多
急性等容血液稀释对兔脑缺血再灌注神经细胞凋亡 s-100β蛋白及炎症因子的影响-effects of acute normovolemic hemodilution on apoptosis s - 100β protein and inflammatory factors in rabbit cerebral ischemia-reperfusion neurons
Effect of acute normovolemic hemodilution on neuronal apoptosis and serum levels of S-100β protein and inflammatory cytokines in the cerebral ischemia reperfusionSpeciality:Anesthesiology Postgraduate:ZhengJinSupervisor:ProfessorHuang Huan-sen Department of Anesthesiology,the second affiliated hospital ofGuangzhou Medical UniversityABSTRACTBackgroundIn clinical, temporarily block parent artery in intracranial aneurysm surgery, regional brain tissue retraction in surgery, myocardial infarction, shock and respiratory and cardiac arrest can cause cerebral ischemia. Cerebral cells are extremely sensitive to ischemia. In order to avoid irreversible damage, timely restoration of cerebral blow flow is necessary. However, the restoration of cerebral blood flow can lead to the ischemia reperfusion injury. Cerebral ischemia reperfusion injury is triggered by a complex cascade of responses, including mitochondria damage, calcium overload, toxic effects of excitatory amino acids, free radicals generation, protease activation, apoptosis gene activation, inflammatory reactions and so on. All these responses reinforce each other, overlap, interrelate and create a vicious cycle ,eventually lead to apoptosis. A large number of studies have shown that cell apoptosis and cerebral ischemia reperfusion injury have a close relationship.Acute inflammatory reaction plays a key role in reperfusion induced secondary braininjury. In cerebral ischemia reperfusion, inflammatory cytokines and proenzymes activated by oxygen free radicals and other messengers induce the release of chemotactic factor, increase of adhesion molecule, and the interactions between leukocyte and endothelial cell. All the above result in leukocyte adhesion to vascular endothelial cell, then the microvascular obstruction happened following to a no-reflow phenomenon. Aggregation of cells release oxygen free radicals, proteolytic enzymes, cytokinins and so on , which directly injury endothelial cells leading to blood-bra
您可能关注的文档
- 极北鲵消化道组织学及其内分泌细胞的分析-analysis of histology and endocrine cells in digestive tract of giant salamander.docx
- 极点配置下执行器增益值的容忍区间研究-research on tolerance intervals of actuator gain value under pole assignment.docx
- 极地与海洋边界层大气微生物含量 种类和粒径分布及其影响因素-species and particle size distribution of atmospheric microorganisms in polar and marine boundary layers and their influencing factors.docx
- 极简主义风格包装设计分析-analysis of minimalist packaging design.docx
- 极简主义风格海报的审美特点--结合毕业设计《爱》的创作体会-aesthetic characteristics of minimalist poster - combining with the creative experience of graduation design love.docx
- 极简主义风格海报的审美特点——结合毕业设计《爱》的创作体会-aesthetic characteristics of minimalist poster —— combining with the creative experience of graduation design.docx
- 极性单体改性st-dvb吸附树脂的孔结构与吸附性能研究-study on pore structure and adsorption properties of st - dvb adsorption resin modified by polar monomers.docx
- 极近距离“三软”薄煤层群沿空留巷配套技术分析-analysis of matching technology of retaining roadways along goaf in extremely close.docx
- 极化效应及其在烃类化合物物理化学性能估算应用-polarization effect and its application in estimating physical and chemical properties of hydrocarbon compounds.docx
- 极小greenschwarz超弦的krr参数化-krr parameterization of minimal green schwarz superstring.docx
- 2024年三支一扶试题含答案详解(夺分金卷).docx
- 2024年三支一扶经典例题(培优B卷)附答案详解.docx
- 2024年三支一扶模拟题库(重点)附答案详解.docx
- 2024年三支一扶题库检测试题打印及完整答案详解【夺冠】.docx
- 2024年三支一扶试题附答案详解【达标题】.docx
- 2024公务员(省考)考前冲刺练习试题【研优卷】附答案详解.docx
- 2024三支一扶复习提分资料及参考答案详解.docx
- 2024三支一扶通关题库含完整答案详解(夺冠).docx
- 2024三支一扶考试历年机考真题集及完整答案详解【全优】.docx
- 2024年三支一扶考前冲刺试卷含答案详解(满分必刷).docx
文档评论(0)