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爆发痛不同止痛给药途径的可行性
Palliative Medicine 2003; 17: 219 / 221
Short report
The acceptability of different routes of administration of
analgesia for breakthrough pain
G Walker, A Wilcock, C Manderson, R Weller and V Crosby Hayward House Macmillan Specialist Palliative
Care Cancer Unit, Nottingham City Hospital NHS Trust, Nottingham, UK
Breakthrough p ain in p atients with cancer is common , RESULTS
often unpredictable and can rapidly become severe. Its
treatment with ora lly administered opioid s may not be One hundred p atients, 48 male, with a mean (range) age
optim al due to th e slow on set of p ain relief. The of 66 (23 / 92) years p articip ated . All found th e ques-
parentera l route provides more rapid on set of p ain relief tio nnaire easy to understand and complete. Patient
but is not always an available, convenient or preferred acceptability of th e different routes varied and appeared
optio n . N ewer routes of analgesic administratio n h ave to be influ enced by previou s experience or expectation of
been or are being developed , such as tra n smucosal, nasal th e u se of th at route and by th e severity of th e p ain (Table
and inh aled, th at aim to combine rapid onset of p ain 1). Age and sex did not appear to influ ence acceptability
relief with convenience.1 Little is known regarding how
and th ese data are not presented .
acceptable p atients view th ese different routes for th e
administr ation of analgesia for breakthrough p ain . To
begin to explore this we undertook this survey. DISCUSSION
This is th e first time th e acceptability of this number
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