the need to know the information needs of parents of infants with an intellectual disability a qualitative study.j adv nurs10.1111jan.131文档.pdf
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the need to know the information needs of parents of infants with an intellectual disability a qualitative study.j adv nurs10.1111jan.131文档
Article
Spatiotemporally Controlled Mechanical Cues Drive
Progenitor Mesenchymal-to-Epithelial Transition
Enabling Proper Heart Formation and Function
Graphical Abstract Authors
Timothy R. Jackson, Hye Young Kim,
Uma L. Balakrishnan,
Carsten Stuckenholz,
Lance A. Davidson
Correspondence
lad43@
In Brief
Jackson et al. describe a mesenchymal-
to-epithelial transition (MET) in heart
progenitor cells that is regulated by
temporally specific mechanical cues
originating from the endoderm.
Accelerating or delaying MET by
manipulating the mechanical
microenvironment of the heart-forming
region leads to abnormal heart anatomy
and function.
Highlights
d Mechanical cues regulate MET in HPCs in early heart
developmen
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