扶正减毒颗粒对放射性肺损伤小鼠肺病理和mmp-2 mmp-9影响的实验研究-experimental study on the effect of fuzheng jiandu granule on lung pathology and mmp - 2 mmp - 9 in mice with radiation-induced lung injury.docx

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扶正减毒颗粒对放射性肺损伤小鼠肺病理和mmp-2 mmp-9影响的实验研究-experimental study on the effect of fuzheng jiandu granule on lung pathology and mmp - 2 mmp - 9 in mice with radiation-induced lung injury.docx

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扶正减毒颗粒对放射性肺损伤小鼠肺病理和mmp-2 mmp-9影响的实验研究-experimental study on the effect of fuzheng jiandu granule on lung pathology and mmp - 2 mmp - 9 in mice with radiation-induced lung injury

over al l st at e.per i pher al bl ood count r esul t s, whi t e bl ood cel l s aft er i rr adi at i on compar ed: cont r ol gr oup and i rr adi at i on gr oup wer e si gni f i cant l y di ff er ent ( p0. 01) , t he r adi at i on gr oup and Chi nese medi ci ne i n t he i nt er vent i on gr oup was st at i st i call y si gni f i cant ( p 0. 05) r ed bl ood cell count showed a bl ank gr oup and i rr adi at i on gr oup wer e si gni f i cant l y di ff er ent ( p 0. 05) , t he r adi at i on gr oup and Chi nese medi ci ne i n t he i nt er vent i on gr oup wer e st at i st i cal l y si gni f i cant ( p 0. 05) .l ung t i ssue vi sual obser vat i on: Chi nese i nt er vent i on gr oup, gr oss obser vat i on at di ff er ent t i me poi nt s l ung swelli ng, r edness, ecchymosi s compar ed wi t h r adi at i on al one gr oup r educed l ung wet wei ght compar ed t o t he t wo gr oups wer e si gni f i cant l y di ff er ent ( p 0. 01) .l ung hi st opat hol ogy obser ved: Chi nese i nt er vent i on gr oup at di ff er ent t i me poi nt s aft er i rr adi at i on, congest i on, edema, i nf l ammat or y r esponse t han si mpl y r educe t he i rr adi at ed gr oup, r ar el y seen i n al veol ar f l ui d, r ed bl ood cell l eakage per uni t ar ea t han t he t wo gr oups di ff er ( p 0. 05 ) ; cont r ol gr oup mi ce l ungs cl ear st r uct ur e and no wi dened al veol ar sept al f i ne.i mmunohi st ochemi cal det er mi nat i on of l ung MMP- 2, MMP- 9 posi t i ve cell s i n t he expr essi on of t he r esul t s: t he r adi at i on gr oup and bl ank gr oup wer e si gni f i cant l y di ff er ent ( P 0. 01) , t r adi t i onal Chi nese medi ci ne i n t he i nt er vent i on gr oup was si gni f i cant l y l ower t han t he expr essi on of posi t i ve cel l s i rr adi at i on gr oup ( P 0. 05) .concl usi on 1 t he mouse l ung t i ssue aft er i rr adi at i on by vi sual obser vat i on