保定市精神病性障碍流行病学调查.docVIP

保定市精神病性障碍流行病学调查 　　【摘要】 目的 了解保定市精神病性障碍的患病率和分布特点。方法 采用多阶段分层整 群抽样方法随机抽取≥18周岁的人群，共10073名，用扩展的一般健康问卷（GHQ-12）将调 查对象分为高、中、低危险组，采用美国精神障碍诊断标准（DSM），以美国精神障碍诊断 与统计手册-第四版（DSM-Ⅳ）轴Ⅰ障碍定式临床检查病人版（SCID-I/P）对调查对象进行 精神病性障碍的诊断。心理、社会及职业功能受损状况评定采用大体功能评定量表（GAF） 评定。结果 9021人完成调查，精神病性障碍的终生患病率为0.74%（95%CI =0.56%～0.92%），时点患病率为0.64%（95%CI=0.48%～0.81%）；精神分裂症最常见，其终 生及时点患病率分别为0.62%、0.54%。时点患病率：女性0.87%高于男性0.42%（P 　　【关键词】 精神病性障碍；流行病学调查；患病率 　　 　　Epidemiological Survey of Psychotic Disorders in Baoding City. Wang Zhan min, Li Xipo. Rongjun Hospital of Hebei, Baoding 071000, P.R.China 　　【Abstract】 Objective To describe the current prevalence and distribu tion of psychotic disorders in Baoding. Methods From Oct.2004 toMar.2005, Stratified multi-stage cluster randomization was used to identify 100 73 subjects aged 18 yea rs or over in Baoding. An expanded version of the General Health Questionnaire ( GHQ-12) was used to identify subjects at high, moderate and low risk for havinga psychotic disorder, then psychiatrists made diagnoses according to the fourthedition of Diagnostic and Statistical Manual of Mental Disorder (DSM-Ⅳ) criteri a after conducting a Structured Clinical Interview for DSM-Ⅳ-TR Axis Ⅰ Disorde rs-Patient Edition (SCID-I/P). The Global Assessment Function (GAF) was used toassess the rate of psychological, social and vocational functional impairment.Results 9021 subjects completed the screening. The overall life time prevalence o f psychotic disorders was 0.74% (95%CI=0.56%～0.92%), and the overall current pr evalence of psychotic disorders was 0.64%(95%CI=0.48%～0.81%); schizophrenia occ upied the first position, and the lifetime and current prevalence of schizophren ia were 0.62% and 0.54% respectively. The overall current prevalence of psychoti c disorders was higher in female (0.87%) than in male (0.42%)(P 　　1.2 方法 　　1.2.1 筛选与诊断工具 以一般健康问卷12项[1]（General Health Questionnai re，GHQ-12）并增加8个心理健康问题为筛选工具，以美国焦虑障碍诊断与统计手册-第4版 （DSM-Ⅳ）轴Ⅰ障碍定式临床检查患者版[2]（Structured Clinical Interview f