儿童太田痣激光治疗回顾性分析.docVIP

儿童太田痣激光治疗回顾性分析 　　[摘要]目的:对激光治疗的儿童太田痣患者进行回顾性随访分析。方法:104例12岁以下儿童太田痣患者,其中男32例,女72例,进行临床特点、激光疗效、不良反应及复发等的临床分析。结果:治疗7次后,颜色和面积的治愈率分别为79.81%和75.96%;治疗10次后,均达到96.15%,再增加治疗次数,治愈率无明显改变;患儿首次治疗年龄越小,达到治愈的治疗次数越少;发病年龄越小越易复发。结论:儿童太田痣早期治疗疗效好,治疗次数少;发病越早的患儿,治疗后越容易复发。 　　[关键词]太田痣;激光;儿童 　　[中图分类号]R758.5+1 [文献标识码]A[文章编号]1008-6455(2010)06-0865-03 　　 　　Retrospective analysis on laser treatment of nevus of Ota in children 　　LIN Tong1, ZHOU Zhan-chao1, GONG Xiang-dong2, WU Yu-le1, YAN Shu-mei1, WU Qiu-ju1, GUO Li-fang1 　　(1.Department of Skin Laser,2.Division of STD Epidemiology, Institute of Dermatology,Chinese Academy of Medical and Sciences, Nanjing 210042, Jiangsu, China) 　　 　　Abstract:ObjectiveTo retrospectively analyse laser treatment of nevus of ota in children.MethodsClinically analyzing characteristics, effects, side effects and recurrence of a hundred and four cases of nevus of ota in children under twelve years old, including thirty-two boys and seventy-two girls.ResultsAfter seven treatments, cure rate of lesion color fade away and size reduce were 79.81% and 75.96% respectively. After ten treatments, both of the two cure rate were 96.15%. After that the cure rate are constant with even more treatments. The younger of first treatment age, the less treatments. The younger age of onset, the higher relapse.ConclusionNevus of ota should be treated as early as possible to reach better efficacy with less treatments. The younger of onset age, the easier recur. 　　Key words: nevus of ota; laser; child 　　 　　太田痣是一种好发于亚洲人颜面部的色素性疾病,大多在出生时或婴儿期发病,部分发生于儿童期,少数在青春期或成年期发病。Q开关激光能够有效治疗太田痣,早已为大家所公认。儿童太田痣激光治疗的效果、不良反应及复发等可能与成人有不同[1],本文对此做一回顾性分析研究。 　　 　　1 临床资料和方法 　　1.1人口统计学资料:回顾性分析在中国医学科学院皮肤病医院诊治并随访7年以上的104例12岁以下太???痣患儿。其中男32例,女72例,男女比例为1:2.25;发病年龄0～10年,平均0.94年;首次治疗年龄2～12年,平均5.5年。其中首次治疗在1岁以内的有29例,占27.9%;1～6岁的有27例,占26%;6岁以上至12岁以下的有48例,占46.2%。 　　1.2临床特征:根据Tanino分型[2],Ⅰ型44例,Ⅱ型42例,Ⅲ型14例,Ⅳ型4例;根据Ueda颜色分级[2],1级棕色35例,2级棕紫色38例,3级紫蓝色20例,4级蓝绿色11例。 　　1.3治疗方法:分别单独用Q开关翠绿宝石(755nm)激光,能量密度5.5～6.0J/cm2治疗;Q开