抗生素PPT课件（英文精品）Post operative Endophthalmitis POE （61p）.ppt

Post operative Endophthalmitis[ POE] Endophthalmitis Endophthalmitis is the clinical term used to describe the inflammatory response of the eye to ocular infection. Classification Endophthalmitis can be classified according to the According to mode of entry Acc to aetiological agents Based on aetiological agents Based on location in the eye When sclera participates ? Panophthalmitis Post-operative endophthalmitis is the most common form. It comprises 70% of infective endophthalmitis Post operative Endophthalmitis (POE) is defined as a severe inflammation involving both the anterior and posterior segments of the eye secondary to an infectious agent. Ophthalmol 2004; 49 (2): S55-S61 Postoperative endophthalmitis May occur after any surgical procedure. Possibility must be considered after any surgical procedure that breaches the integrity of the corneo-scleral wall of the eye, no matter how ‘minor’ the breach may be Large majority follow cataract surgery, most common surgical procedure (approx prevalence 0.082%- 0.1%) Post- operative endophthalmitis is one of the most dreaded complications of cataract surgery and constitutes a true emergency. Incidence of postoperative endophthalmitis Worldwide, the reported incidence of post-op endophthalmitis is 0.04-4%. In India, Incidence varies from 0.07-0.3% POE: A potentially blinding condition Though rare, it is potentially the most devastating complication of intraocular procedures and can lead to a permanent, complete loss of vision. (animal studies confirm that the retina begins to necrose very quickly in endophthalmitis) Endophthalmitis has been associated with severe visual loss in 20% of patients. Post-op endophthalmitis: causes Periocular flora gain access into eye during surgery Organisms may be carried into the eye as surface fluid refluxes through the wound during surgery IOL contamination if it touches the ocular surface or with the air of the operating room Contaminated irrigat