后路椎体间自体骨融合与Cage融合治疗下腰椎不稳临床对照研究.docVIP

后路椎体间自体骨融合与Cage融合治疗下腰椎不稳临床对照研究 　　[摘要] 目的 比较在椎弓根螺钉固定基础上后路椎体间自体骨融合与Cage融合治疗下腰椎不稳的疗效。 方法 采用随机分组的方法，将2009年1月～2010年6月间本院收治的48例下腰椎不稳的患者分为两组，研究组24例在椎弓根螺钉固定基础上行后路椎体间自体骨融合，对照组24例在椎弓根螺钉固定基础上行后路椎体间Cage融合，比较两组患者的治疗效果。 结果 两组患者出血量、手术时间、住院时间、腰背痛手术评分、并发症发生率和融合率差异无统计学意义（P 0.05）；而研究组椎间隙高度明显低于对照组，差异有统计学意义（P 　　[关键词] 下腰椎不稳；自体骨融合；Cage融合；椎弓根螺钉固定 　　[中图分类号] R687.3 [文献标识码] B [文章编号] 1673-9701（2012）30-0038-02 　　Posterior lumbar interbody fusion with autologous bone or cage for treatment of instability of lower lumbar： A prospective randomized controlled study 　　GU Shaofei FAN Yajun 　　Department of Orthopedics， the Peoples Hospital of Ganyu County in Jiangsu Province， Ganyu 222100， China 　　[Abstract] Objective To compare clinical efficacy of posterior lumbar interbody fusion by using autologous bone or cage for treatment of instability of lower lumbar on the basis of the pedicle screw fixation. Methods By using randomized controlled trail， 48 patients with instability of lower lumbar who stayed and were treated in our hospital were divided into control group （24 cases） and study group （24 cases） from January 2009 to June 2010. Cases in study group were given the therapy of posterior lumbar interbody fusion with autologous bone on the basis of the pedicle screw fixation system， whereas cases in control group were given the therapy of posterior lumbar interbody fusion with cage on the basis of the pedicle screw fixation system. Observed and compared the efficacy between two groups. Results The significant difference of blood loss， operative time， hospital stay， JOA score， incidence rate of complication and fusing rate was not founded between two groups （P all 0.05）. The intervertebral space height in study group was significantly lower than that in control group， and there was significant difference between two groups. Conclusion The posterior lumbar interbody fusion can be used for treatment of adult instability of lower lumbar just like cage fusing. But compared with cage fusing， there is