抗生素优化理4幻灯片.ppt

What is AB Stewardship? An approach to promote evidence based usage of antibiotics to reduce resistance improve outcome. The program assists participating hospitals in developing customized ‘Treatment Guidelines’ based on the hospital’s ecology microbiology data. Antibiotic Stewardship goes beyond traditional doctor detailing to influence all stakeholders in a hospital Key Benefits of Antibiotic Stewardship Program Benefit to Patients : To optimise clinical outcome in patients with infection Benefit to Doctors: Better quality therapeutic decisions based on evidence Benefit to Society: To try and reduce the antimicrobial resistance and improve hospital ecology To reduce the total health care cost Infectious Diseases Expert Resources IVZ 2005-W-226381-SS Slide * Once a pathogen produces infection, antimicrobial treatment may be essential However, antimicrobial use promotes selection of antimicrobial-resistant strains of pathogens As the prevalence of resistant strains increases in a population, subsequent infections are increasingly likely to be caused by these resistant strains Fortunately, this cycle of emerging antimicrobial resistance/multidrug resistance can be interrupted Preventing infections in the first place will certainly reduce the need for antimicrobial exposure and the emergence and selection of resistant strains Effective diagnosis and treatment will benefit the patient and decrease the opportunity for development and selection of resistant microbes; this requires rapid accurate diagnosis, identification of the causative pathogen, and determination of its antimicrobial susceptibility Optimizing antimicrobial use is another key strategy; optimal use will ensure proper patient care and at the same time avoid overuse of broad-spectrum antimicrobials and unnecessary treatment Finally, preventing transmission of resistant organisms from one person to another is critical to successful prevention efforts * CMK Ref 1, p 3, C2, Bullets 2, 3 Re