孤独症颅脑MRI研究进展2017813.pptx

孤独症颅脑MRI研究进展;Brain MRI research progress in autism;前言;目录;目录;1. 孤独症简介;孤独症的首次发现;诊断标准的演变;DSM-V（2013）;DSM-V;DSM-V;[1] Coplan J. Atypicality, intelligence, and age: a conceptual model of autistic spectrum disorder. Dev Med Child Neurol, 2003, 45(10): 712-716. [2] Coplan J, Jawad AF. Modeling clinical outcome of children with autistic spectrum disorders. Pediatrics, 2005, 116(1): 117-122. ;[1] Coplan J. Atypicality, intelligence, and age: a conceptual model of autistic spectrum disorder. Dev Med Child Neurol, 2003, 45(10): 712-716. [2] Coplan J, Jawad AF. Modeling clinical outcome of children with autistic spectrum disorders. Pediatrics, 2005, 116(1): 117-122. ;孤独症的诊断;目录;[1] Wakefield AJ, Murch SH, Anthony A, et al. Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet, 1998, 351(9103): 637-641. ;[1] Wakefield AJ, Murch SH, Anthony A, et al. Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children. Lancet, 1998, 351(9103): 637-641. ;[1] Pinto D, Delaby E, Merico D, et al. Convergence of genes and cellular pathways dysregulated in autism spectrum disorders. Am J Hum Genet, 2014, 94(5): 677-694. ;[1] Szoko N, McShane AJ, Natowicz MR. Proteomic explorations of autism spectrum disorder. Autism Res, 2017.;截止至2017-8-6 Pubmed上关于autism 以及autism MRI 的文献数;目录;早期MRI研究;秦志宏,1996;[1] Courchesne E, Press GA, Yeung-Courchesne R. Parietal lobe abnormalities detected with MR in patients with infantile autism. AJR Am J Roentgenol, 1993, 160(2): 387-393. ;[1] Schifter T, Hoffman JM, Hatten HP, Jr., et al. Neuroimaging in infantile autism. J Child Neurol, 1994, 9(2): 155-161. ;[1] Courchesne E, Saitoh O, Yeung-Courchesne R, et al. Abnormality of cerebellar vermian lobules VI and VII in patients with infantile autism: identification of hypoplastic and hyperplastic subgroups with MR imaging. AJR Am J Roentgenol, 1994, 162(1): 123-130.;00’sMRI研究;TBV;基于体素的DTI研究;大脑的不对称性;胼胝体;DTI of CC;[1]