淋巴瘤解读课件.pptVIP

2008年淋巴瘤新分类解读 南昌大学医学院病理教研室 刘繁荣 WHO (2008) “造血和淋巴组织肿瘤性疾病”新分类 定义淋巴瘤每个独立疾病或类型 必须结合 ●形态改变 ●免疫表型 ●遗传特征 ●临床表现 好好一笔字让电脑毁了 * “世界淋巴瘤宣传日”发起 国际淋巴瘤联盟、WHO 日期 2004起 每年9月15日目的 帮助人们识别淋巴瘤早期症状,做到 早发现、治疗，提高患者存活率 淋巴瘤？淋巴样系统恶性肿瘤 近年发病率↑↑ 新发病例 全球 30万/每年 Diagnosis Morphology Clinical features Immunologic and biologic markers 好好一个病理大夫 让淋巴瘤毁了 WHO Classification 2008 2004: Successful protest of the ILSG against the WHO decision to stop printing of pathology classifications or to update them; 2004: Formation of the Steering Committee (SC) consisting of 7 expert hematopathologists, two from Germany (Jürgen Thiele and Harald Stein) by the EAHP and the (American) SH; 2005-2006: Discussion of classification concepts and appointing 75 expert hematologists as authors for the different diseases; 2007 March: Discussion of classification concepts with clinicians at the CAC meeting 2007 April-September: Preparation of the description of the lymphoma disorders by the authors; 2007 October: 3 day Consensus meeting at the IARC* in Lyon; 2008 July: finishing the descriptions according to the consensus; 2008 September: publication of the blue 2008 WHO classification * IARC = International Agency for Research on Cancer S. Swerdlow E. Campo Nancy.L. Harris Elaine.S. Jaffe S.A. Pileri H. Stein J. Thiele J.W. Vardimann and numerous other lymphoma experts 2008 WHO Classification of lymphoid neoplasms 2008 WHO Classification of myeloid neoplasms *