丝虫肝吸虫姜片虫肺吸虫血吸虫课件.ppt

Chinese Liver Fluke or Oriental Liver fluker Found from the biliary passage of a Chinese in Calcutta, India in 1874 firstly. Common in Asia (China, Korea and Japan) Clonorchiasis (肝吸虫病) In the acute phase, abdominal pain, nausea, diarrhea, and eosinophilia can occur. In long-standing infections, cholangitis, cholelithiasis, pancreatitis, and cholangiocarcinoma can develop, which may be fatal. Finding eggs in the feces (egg-concentration method ,深沉集卵法) Finding eggs in duodenal aspirate Infection source: human ,dogs,cats and rats Eggs are passed into water First and second intermediate host in water Eating raw fish with metacercariae(囊蚴) Praziquantel and albendazole has proven of value. Fish should be cooked well before consumption. Feces must be treated before disposal. The largest intestinal fluke of humans . A parasite of central and southeast Asia. 130 to 159 μm by 78 to 98 μm ellipsoidal indistinct operculum thin shell undeveloped germinal cell Physical injury to the intestinal mucosa Metabolic product Allergic reaction Most infections are light and asymptomatic In heavier infections, symptoms include diarrhea, abdominal pain, fever, ascites, anasarca and intestinal obstruction. Microscopic identification of eggs, or more rarely of the adult flukes, in the stool or vomitus. Asia and the Indian subcontinent Especially in areas where humans raise pigs and consume freshwater plants. Change food habits Praziquantel is the drug of choice . Paragonimus 50 species of paragonimus, P. westermani (the oriental lung fluke) is the most important 1878, first description in tiger; in 1880, first case found in Taiwan Paragonimiasis (parasitic zoonoses) Paragonimus westermani adult: a plump reddish brown oval worm measuring 10 by 4 mm . Average size :85 μm by 53 μm Yellow-brown, ovoidal or elongate Thickshell ,asymmetrical Operculum is clearly visible Finding eggs in stool or sputum. (直接涂片法) Finding larvae in tissue